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BAG3 Produits

(BCL2-Associated Athanogene 3 (BAG3))
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008].

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Catégories BAG3 en vedette

BAG3 Anticorps

High quality antibodies with extensive validation data.

BAG3 Kits ELISA

Reliable ELISA kits for a wide range of species.

BAG3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BAG3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (5)
N° du produit ABIN7258158
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
N° du produit ABIN184770
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (4)
N° du produit ABIN7265851
Quantité 100 μL
Fiche technique Fiche technique

BAG3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6954056
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962016
Quantité 96 tests
Fiche technique Fiche technique

BAG3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1346366
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3089978
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3130338
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits BAG3

Li, Chen, Cao, Li, Zhao, Zhai, Ren, Li: "Bcl-2-associated athanogene 3(BAG3) is associated with tumor cell proliferation, migration, invasion and chemoresistance in colorectal cancer." dans: BMC cancer, Vol. 18, Issue 1, pp. 793, (2019) (PubMed).

Toro, Pérez-Serra, Campuzano, Moncayo-Arlandi, Allegue, Iglesias, Mangas, Brugada: "Familial Dilated Cardiomyopathy Caused by a Novel Frameshift in the BAG3 Gene." dans: PLoS ONE, Vol. 11, Issue 7, pp. e0158730, (2016) (PubMed).

Kundu, Milosch, Antonietti, Baumkötter, Zymny, Müller, Kins, Hajieva, Behl, Kögel: "Modulation of BAG3 Expression and Proteasomal Activity by sAPPα Does Not Require Membrane-Tethered Holo-APP." dans: Molecular neurobiology, (2015) (PubMed).

Nymoen, Hetland Falkenthal, Holth, Ow, Ivshina, Tropé, Kuznetsov, Staff, Davidson: "Expression and clinical role of chemoresponse-associated genes in ovarian serous carcinoma." dans: Gynecologic oncology, Vol. 139, Issue 1, pp. 30-9, (2015) (PubMed).

Nishikawa, Okuzaki, Fukushima, Mukai, Ohno, Ozaki, Yabuta, Nojima: "Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0134137, (2015) (PubMed).

dAvenia, Citro, De Marco, Veronese, Rosati, Visone, Leptidis, Philippen, Vitale, Cavallo, Silverio, Prota, Gravina, De Cola, Carletti, Coppola, Gallo, Provenza, Bossone, Piscione, Hahne, De Windt et al.: "A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy. ..." dans: Cell death & disease, Vol. 6, pp. e1948, (2015) (PubMed).

Pacheco, Berra, Morais, Sciani, Branco, Bosch, Chudzinski-Tavassi: "Dynein function and protein clearance changes in tumor cells induced by a Kunitz-type molecule, Amblyomin-X." dans: PLoS ONE, Vol. 9, Issue 12, pp. e111907, (2014) (PubMed).

Chen, Yang, Cheng, Tu, Guo, Le, Xiong, Mo, Li, Jeong, Jiang, Blackshaw, Bi, Zhu, Tao, Ge: "Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2804-19, (2013) (PubMed).

Aust, Pils, Polterauer, Horvat, Cacsire Castillo-Tong, Pils, Dudek, Schmid, Speiser, Reinthaller, Grimm: "Expression of Bcl-2 and the antiapoptotic BAG family proteins in ovarian cancer." dans: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 21, Issue 6, pp. 518-24, (2013) (PubMed).

Goldman, Chen, Roesly, Hill, Tome, Dvorak, Bernstein, Dvorak: "Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 300, Issue 2, pp. G292-302, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à BAG3

BCL2 associated athanogene 3 L homeolog (bag3.L), BCL2-associated athanogene 3 (bag3), BCL2 associated athanogene 3 (BAG3), BCL2 associated athanogene 3 (bag3), BCL-2-associated athanogene 3 (BAG3), BCL2-associated athanogene 3 (Bag3), Bcl2-associated athanogene 3 (Bag3), AA407278, ATBAG3, BAG-3, BAG3, bag3-A, BCL-2-associated athanogene 3, BIS, Bis, CAIR-1, MFM6, mg638, MGC53113, T28J14.160, T28J14_160, zgc:100859

Protein level used designations for BAG3

  • BCL2-associated athanogene 3
  • BAG family molecular chaperone regulator 3
  • BAG family molecular chaperone regulator 3-like
  • BCL2-binding athanogene 3
  • bcl-2-binding protein Bis
  • docking protein CAIR-1
  • BAG-3
  • Bcl-2-binding protein Bis
  • Bcl-2-interacting death suppressor
  • bcl-2-associated athanogene 3
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