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BAD Produits

(BCL2-Associated Agonist of Cell Death (BAD))

Catégories

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008].

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Catégories BAD en vedette

BAD Anticorps

High quality antibodies with extensive validation data.

BAD Kits ELISA

Reliable ELISA kits for a wide range of species.

BAD Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BAD recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro)
Validations
  • (3)
  • (1)
N° du produit ABIN674709
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (8)
N° du produit ABIN7443224
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
N° du produit ABIN5542486
Quantité 0.1 mg
Fiche technique Fiche technique

BAD recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965132
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965131
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965127
Quantité 96 tests
Fiche technique Fiche technique

BAD recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346356
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1775808
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3122934
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits BAD

Mega Tiber, Kocyigit Sevinc, Kilinc, Orun: "Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562." dans: Gene, Vol. 692, pp. 217-222, (2019) (PubMed).

Lu, Zhang, Tan, Luo, Zhao, Ma, Liang, Tan: "GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia." dans: International journal of molecular medicine, Vol. 38, Issue 1, pp. 105-12, (2017) (PubMed).

Hu, Kuo, Senadi, Chang, Wang: "Photodynamic Therapy Using Indolines-Fused-Triazoles Induces Mitochondrial Apoptosis in Human Non-Melanoma BCC Cells." dans: Anticancer research, Vol. 37, Issue 10, pp. 5499-5505, (2017) (PubMed).

Mishra, Thakur, Somal, Parmar, Yadav, Bharati, Bharti, Paul, Verma, Chouhan, Sharma, Singh, González, DOcchio, Sarkar et al.: "Expression and localization of angiopoietin family in buffalo ovarian follicles during different stages of development and modulatory role of angiopoietins on steroidogenesis and survival of cultured ..." dans: Theriogenology, Vol. 86, Issue 7, pp. 1818-33, (2016) (PubMed).

Mishra, Parmar, Yadav, Reshma, Bharati, Bharti, Paul, Chouhan, Taru Sharma, Singh, Sarkar et al.: "Expression and localization of angiopoietin family in corpus luteum during different stages of oestrous cycle and modulatory role of angiopoietins on steroidogenesis, angiogenesis and survivability ..." dans: Reproduction in domestic animals = Zuchthygiene, Vol. 51, Issue 6, pp. 855-869, (2016) (PubMed).

Shan, Yan, Diao, Lin, Wang, Zhang, Zhang, Wei: "Involvement of caspases and their upstream regulators in myocardial apoptosis in a rat model of selenium deficiency-induced dilated cardiomyopathy." dans: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), Vol. 31, pp. 85-91, (2015) (PubMed).

Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).

Huang, Liu, Chen, Zeng, Wang, Zhang, Mo, Li: "Loss of Bad expression confers poor prognosis in non-small cell lung cancer." dans: Medical oncology (Northwood, London, England), Vol. 29, Issue 3, pp. 1648-55, (2012) (PubMed).

Gan, Chen, Zhong, Wang, Lam, Liu, Zhang, Zhou, Yu, Si, Wang, Jin: "ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer." dans: PLoS ONE, Vol. 6, Issue 2, pp. e16916, (2011) (PubMed).

Polzien, Baljuls, Albrecht, Hekman, Rapp: "BAD contributes to RAF-mediated proliferation and cooperates with B-RAF-V600E in cancer signaling." dans: The Journal of biological chemistry, Vol. 286, Issue 20, pp. 17934-44, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à BAD

BCL2-associated agonist of cell death b (badb), BCL2 associated agonist of cell death (BAD), BCL2-associated agonist of cell death (Bad), AI325008, bad, BAD, BBC2, Bbc2, BCL2L8, fa01b12, wu:fa01b12, wu:fa96d04

Protein level used designations for BAD

  • proapoptotic BH3-only protein
  • BCL2-antagonist of cell death
  • BCL2-associated agonist of cell death
  • BCL-X/BCL-2 binding protein
  • BCL2-antagonist of cell death protein
  • BCL2-binding component 6
  • BCL2-binding protein
  • bcl-2-binding component 6
  • bcl-2-like protein 8
  • bcl-XL/Bcl-2-associated death promoter
  • bcl2 antagonist of cell death
  • bcl2-L-8
  • Bcl-associated death promoter
  • bcl-xL/Bcl-2-associated death promoter
  • Bcl2-antagonist of cell death
  • bcl-2 associated death agonist
  • bcl2-associated death promoter
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