BRE Protéines
(Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and modulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin (By similarity).
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custom-made
BRE
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
BRE
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
BRE
Origine: Humain
Hôte: Wheat germ
Recombinant
ELISA, WB, AA, AP
1 image
custom-made
BRE
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
BRE
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
ELISA, WB, SDS
custom-made
BRE
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
BRE
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 80 % as determined by SDS-PAGE.
ELISA, WB
BRE
Origine: Saguinus oedipus
Hôte: Levure
Recombinant
> 90 %
ELISA
BRE
Origine: Branchiostoma floridae
Hôte: Levure
Recombinant
> 90 %
ELISA
BRE
Origine: Poisson zèbre (Danio rerio)
Hôte: Levure
Recombinant
> 90 %
ELISA
BRE
Origine: Xenopus tropicalis
Hôte: Levure
Recombinant
> 90 %
ELISA
BRE
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
ELISA, WB, SDS, Imm
Pseudonymes pour BRE Protéines
BRISC and BRCA1 A complex member 2 (babam2) ProtéinesBRISC and BRCA1 A complex member 2 (BABAM2) Protéines
BRISC and BRCA1 A complex member 2 (Babam2) Protéines
brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE) Protéines
BRISC and BRCA1 A complex member 2 L homeolog (babam2.L) Protéines
6030405P19Rik Protéines
AI429776 Protéines
B830038C02Rik Protéines
brcc4 Protéines
BRCC4 Protéines
brcc45 Protéines
BRCC45 Protéines
BRE Protéines
im:7141046 Protéines
LOC100231620 Protéines
zgc:110368 Protéines
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