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CACNA1G Produits

(Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Catégories

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011].

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Catégories CACNA1G en vedette

CACNA1G Anticorps

High quality antibodies with extensive validation data.

CACNA1G Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CACNA1G recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN680608
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN1027719
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN2483303
Quantité 100 μg
Fiche technique Fiche technique

CACNA1G recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6213224
Quantité 96 tests
Fiche technique Fiche technique

CACNA1G recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3090206
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3090207
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3090208
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CACNA1G

Curran, Musa, Kline, Makara, Little, Higgins, Hund, Band, Mohler: "Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria." dans: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12210-21, (2015) (PubMed).

Lu, Long, Zhou, Xu, Hu, Li: "Mibefradil reduces blood glucose concentration in db/db mice." dans: Clinics (São Paulo, Brazil), Vol. 69, Issue 1, pp. 61-7, (2014) (PubMed).

Borahay, Kilic, Yallampalli, Snyder, Hankins, Al-Hendy, Boehning: "Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells." dans: The Journal of biological chemistry, Vol. 289, Issue 51, pp. 35075-86, (2014) (PubMed).

Rice, Berchtold, Cotman, Green: "Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production." dans: Neurobiology of aging, Vol. 35, Issue 5, pp. 1002-11, (2014) (PubMed).

Valerie, Dziegielewska, Hosing, Augustin, Gray, Brautigan, Larner, Dziegielewski: "Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells." dans: Biochemical pharmacology, Vol. 85, Issue 7, pp. 888-97, (2013) (PubMed).

Puthussery, Venkataramani, Gayet-Primo, Smith, Taylor: "NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 41, pp. 16045-59, (2013) (PubMed).

Strandberg, Cui, Rath, Liu, Silverman, Liu, Siragam, Ackerley, Su, Yan, Capecchi, Biavati, Accorroni, Yuen, Quattrone, Lung, Jaeggi, Backx, Deber, Hamilton: "Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts." dans: PLoS ONE, Vol. 8, Issue 9, pp. e72668, (2013) (PubMed).

Goonasekera, Hammer, Auger-Messier, Bodi, Chen, Zhang, Reiken, Elrod, Correll, York, Sargent, Hofmann, Moosmang, Marks, Houser, Bers, Molkentin: "Decreased cardiac L-type Ca²? channel activity induces hypertrophy and heart failure in mice." dans: The Journal of clinical investigation, Vol. 122, Issue 1, pp. 280-90, (2012) (PubMed).

Ernst, Zhang, Yoo, Ernst, Noebels: "Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 6, pp. 1615-25, (2009) (PubMed).

Sohal, Huguenard: "It takes T to tango." dans: Neuron, Vol. 31, Issue 1, pp. 3-4, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à CACNA1G

calcium voltage-gated channel subunit alpha1 G (CACNA1G), calcium channel, voltage-dependent, T type, alpha 1G subunit (cacna1g), calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog (cacna1g.L), calcium channel, voltage-dependent, T type, alpha 1G subunit (Cacna1g), calcium voltage-gated channel subunit alpha1 G (Cacna1g), a1G, alpha-1G, ca(v)3.1, Ca(v)3.1, Ca(V)T.1, CACNA1G, cav3.1, Cav3.1, Cav3.1d, mKIAA1123, NBR13, [a]1G

Protein level used designations for CACNA1G

  • voltage-dependent calcium channel alpha 1G subunit
  • calcium channel, voltage-dependent, T type, alpha 1G subunit
  • calcium channel voltage-dependent T type Cav3.1, alpha 1g subunit
  • cav3.1c
  • voltage-dependent T-type calcium channel subunit alpha-1G
  • voltage-gated calcium channel subunit alpha Cav3.1
  • calcium channel, voltage-dependent, alpha 1G subunit
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