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CAMKK2 Produits

(Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Catégories

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012].

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Catégories CAMKK2 en vedette

CAMKK2 Anticorps

High quality antibodies with extensive validation data.

CAMKK2 Kits ELISA

Reliable ELISA kits for a wide range of species.

CAMKK2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CAMKK2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (1)
  • (6)
N° du produit ABIN564643
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (1)
  • (4)
N° du produit ABIN950067
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (5)
  • (2)
N° du produit ABIN1882069
Quantité 400 μL
Fiche technique Fiche technique

CAMKK2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965332
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6954286
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5593540
Quantité 96 tests
Fiche technique Fiche technique

CAMKK2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1347947
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1347949
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093354
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CAMKK2

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." dans: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Ma, Wen, Wang, Yang, Liu, Liu, Zhu, Fang et al.: "Growth inhibition of human gastric adenocarcinoma cells in vitro by STO-609 is independent of calcium/calmodulin-dependent protein kinase kinase-beta and adenosine monophosphate-activated protein ..." dans: American journal of translational research, Vol. 8, Issue 2, pp. 1164-71, (2016) (PubMed).

Zhao, Zhang, Liu, Zhang, Hao, Li, Chen, Shen, Tang, Min, Meng, Wang, Yi, Zhang: "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." dans: Scientific reports, Vol. 6, pp. 37884, (2016) (PubMed).

Wang, Zhao, Yu, Feng, Zhang, Kou, Chu, Cui, Li, Zhang, Shen, Min: "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." dans: Toxicology and applied pharmacology, Vol. 313, pp. 149-158, (2016) (PubMed).

Krishan, Richardson, Sahni: "The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells." dans: Biochimica et biophysica acta, Vol. 1863, Issue 12, pp. 2916-2933, (2016) (PubMed).

Wang, Zhang, Liang, Zhang, Xu, Zhang, Fuji, Mu, Li, Jiang, Ju, Wang: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." dans: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).

Karacosta, Foster, Azabdaftari, Feliciano, Edelman: "A regulatory feedback loop between Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) and the androgen receptor in prostate cancer progression." dans: The Journal of biological chemistry, Vol. 287, Issue 29, pp. 24832-43, (2012) (PubMed).

Massie, Lynch, Ramos-Montoya, Boren, Stark, Fazli, Warren, Scott, Madhu, Sharma, Bon, Zecchini, Smith, Denicola, Mathews, Osborne, Hadfield, Macarthur, Adryan, Lyons, Brindle, Griffiths, Gleave et al.: "The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis. ..." dans: The EMBO journal, Vol. 30, Issue 13, pp. 2719-33, (2011) (PubMed).

Kou, Sartoretto, Michel: "Regulation of Rac1 by simvastatin in endothelial cells: differential roles of AMP-activated protein kinase and calmodulin-dependent kinase kinase-beta." dans: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 14734-43, (2009) (PubMed).

Goravanahally, Salem, Yao, Inskeep, Flores: "Differential gene expression in the bovine corpus luteum during transition from early phase to midphase and its potential role in acquisition of luteolytic sensitivity to prostaglandin F2 alpha." dans: Biology of reproduction, Vol. 80, Issue 5, pp. 980-8, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à CAMKK2

calcium/calmodulin dependent protein kinase kinase 2 (CAMKK2), calcium/calmodulin-dependent protein kinase kinase 2, beta (Camkk2), calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 (camk2b1), calcium/calmodulin dependent protein kinase II beta (CAMK2B), calcium/calmodulin-dependent protein kinase kinase 2, beta (camkk2), calcium/calmodulin-dependent protein kinase kinase 2 (Camkk2), calcium/calmodulin dependent protein kinase kinase 2 (Camkk2), 6330570N16Rik, AW061083, camk2b, CAMKK, CAMKK2, CAMKKB, fj90d04, mKIAA0787, si:dkey-174n20.2, wu:fj90d04

Protein level used designations for CAMKK2

  • CAMKK beta protein
  • caM-KK 2
  • caM-KK beta
  • caM-kinase kinase 2
  • caM-kinase kinase beta
  • calcium/calmodulin-dependent protein kinase beta
  • calcium/calmodulin-dependent protein kinase kinase 2
  • caMKK 2
  • caMKK beta
  • calcium/calmodulin-dependent protein kinase kinase beta
  • calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
  • protein-tyrosine kinase
  • calcium/calmodulin-dependent protein kinase II beta
  • calcium/calmodulin-dependent protein kinase kinase 2, beta
  • calcium/calmodulin-dependent protein kinase kinase 2-like
  • Ca+/Calmodulin-dependent protein kinase kinase beta (CaM-kinase kinase beta)
  • CaM-kinase kinase beta
  • calcium/calmodulin-dependent protein kinase 2 beta
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