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CCM2 Protéines

(Cerebral Cavernous Malformation 2 (CCM2))

This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009].

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CCM2 Protein (AA 1-453) (His tag)

custom-made CCM2 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Ccm2 Protein, UniprotID Q8K2Y9

3 images

N° du produit ABIN7559524

Détails

CCM2 Protein (AA 1-444) (His tag)

custom-made CCM2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant CCM2 Protein, UniprotID Q9BSQ5

3 images

N° du produit ABIN7552982

Détails

CCM2 Protein (AA 66-353) (His-IF2DI Tag)

CCM2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

Western Blotting (WB) image for Cerebral Cavernous Malformation 2 (CCM2) (AA 66-353) protein (His-IF2DI Tag) (ABIN7122246)

1 image

N° du produit ABIN7122246

Détails

CCM2 Protein (AA 1-444) (GST tag)

CCM2 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP

Image no. 1 for Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) protein (GST tag) (ABIN1348424)

1 image

N° du produit ABIN1348424

Détails

CCM2 Protein (AA 66-353) (His tag)

CCM2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS

SDS-PAGE (SDS) image for Cerebral Cavernous Malformation 2 (CCM2) (AA 66-353) protein (His tag) (ABIN5853462)

SDS

1 image

N° du produit ABIN5853462

Détails

CCM2 Protein (His tag)

CCM2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE

N° du produit ABIN1589765

Détails

CCM2 Protéine

CCM2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % pure SDS

N° du produit ABIN2128400

Détails

CCM2 Protein (AA 1-453) (Strep Tag)

custom-made CCM2 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3126365

Détails

CCM2 Protein (AA 1-444) (Strep Tag)

custom-made CCM2 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3090690