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CD276 Protéines

(CD276)
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

47 Résultats

CD276 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
N° du produit ABIN7273951
 
CD276 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7273957
 
CD276 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7273969
 
CD276 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
N° du produit ABIN6961085
 
CD276 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7273972
 
CD276 Origine: Souris Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7092853
 
CD276 Origine: Humain Hôte: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
N° du produit ABIN4369856
 
CD276 Origine: Humain Hôte: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
N° du produit ABIN1348596
 
CD276 Origine: Humain Hôte: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
N° du produit ABIN1348594
 
CD276 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
N° du produit ABIN5954964
 
CD276 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
N° du produit ABIN5674582
 
CD276 Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by SDS-PAGE
N° du produit ABIN7320471
 
CD276 Origine: Cynomolgus Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7320967
 
CD276 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7490943
 
CD276 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7122199
 
CD276 Origine: Cynomolgus Hôte: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7538169
 
CD276 Origine: Rat Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
N° du produit ABIN7321098
 
CD276 Origine: Rat Hôte: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
N° du produit ABIN7321099
 
CD276 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
N° du produit ABIN7273960
 
CD276 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN6938824
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Protein Interaction (PI)
    • Activity Assay (AcA)
    • Antibody Production (AbP)
    • Positive Control (PC)
    • Standard (STD)
    • Cell Culture (CC)
  • Réactivité
    • Human
    • Mouse
    • Cynomolgus
    • Rat
  • Images disponible
  • Carrier free only
  • Hote
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • CHO Cells
    • HEK-293T Cells
    • Mammalian Cells
    • Human Cells
    • Baculovirus infected Insect Cells
  • Epitope
    • AA 29-245
    • AA 27-461
    • partial
    • AA 29-244
    • AA 29-248
    • AA 29-461
    • AA 29-465
    • AA 47-219
    • AA 140-248
    • AA 237-461
    • AA 28-140
    • AA 28-238
    • AA 29-144
    • AA 30-248
    • AA 30-466
    • AA 47-213
    • Transcript Variant 2
  • Conjugué
    • His tag
    • Fc Tag
    • His-DYKDDDDK-Strep II Tag
    • Inconjugué
    • DYKDDDDK-His Tag
    • FITC,Fc Tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,His tag
    • His tag,AVI tag,Biotin
    • His-Avi Tag,Biotin
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
    • mFc Tag
    • mFc-His Tag
  • Type Proteine
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Activité biologique
    • Biologically Active
    • Biologically Inactive
  • Supplier
    • antibodies-online
    • ProSci
    • ACROBiosystems
    • OriGene
    • Cloud-Clone

Dernières publications pour nos CD276 Protéines

Wang, Ma, Zhan, Zhang, Cao, Zhang, Shi, Chen: "B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression." dans: Cell death & disease, Vol. 11, Issue 1, pp. 55, (2020) (PubMed).

Stern, Lown, Kobe, Abou-Elkacem, Willmann, Hackel: "Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276." dans: ACS combinatorial science, Vol. 21, Issue 3, pp. 207-222, (2020) (PubMed).

Du, Hirabayashi, Ahn, Kren, Montgomery, Wang, Tiruthani, Mirlekar, Michaud, Greene, Herrera, Xu, Sun, Chen, Ma, Ferrone, Pylayeva-Gupta, Yeh, Liu, Savoldo, Ferrone, Dotti: "Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells." dans: Cancer cell, Vol. 35, Issue 2, pp. 221-237.e8, (2019) (PubMed).

Gong, Kiyotani, Sakata, Nagano, Kumehara, Baba, Besse, Yanagitani, Friboulet, Nishio, Takeuchi, Kawamoto, Fujita, Katayama: "Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer." dans: The Journal of experimental medicine, Vol. 216, Issue 4, pp. 982-1000, (2019) (PubMed).

Pseudonymes pour CD276 Protéines

CD276 molecule (CD276) Protéines
CD276 molecule S homeolog (cd276.S) Protéines
CD276 molecule (cd276) Protéines
CD276 antigen (Cd276) Protéines
Cd276 molecule (Cd276) Protéines
4Ig-B7-H3 Protéines
6030411F23Rik Protéines
AU016588 Protéines
B7-H3 Protéines
B7h3 Protéines
B7H3 Protéines
B7RP-2 Protéines
sc:d0645 Protéines
zgc:158279 Protéines
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