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CD40 Produits

(CD40)

Catégories

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Catégories CD40 en vedette

CD40 Anticorps

High quality antibodies with extensive validation data.

CD40 Kits ELISA

Reliable ELISA kits for a wide range of species.

CD40 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CD40 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
N° du produit ABIN7442747
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN3020704
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application FACS, IHC, IF, StM, DNA Mic
Validations
  • (5)
N° du produit ABIN6941185
Quantité 100 μg
Fiche technique Fiche technique

CD40 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954519
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954518
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954520
Quantité 96 tests
Fiche technique Fiche technique

CD40 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7274186
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274177
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274188
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CD40

Upadhyaya, Lahdenranta, Hurov, Battula, Dods, Haines, Kleyman, Kristensson, Kublin, Lani, Ma, Mudd, Repash, Van Rietschoten, Stephen, You, Harrison, Chen, McDonnell, Brandish, Keen: "Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist." dans: Journal for immunotherapy of cancer, Vol. 9, Issue 1, (2021) (PubMed).

Toka, Dunaway, Smaltz, Szulc-Dąbrowska, Drnevich, Mielcarska, Bossowska-Nowicka, Schweizer: "Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell line." dans: BMC genomics, Vol. 20, Issue 1, pp. 15, (2019) (PubMed).

Duarte, Cragnolini, Swee, Bilate, Bader, Ingram, Rashidfarrokhi, Fang, Schiepers, Hanke, Ploegh: "Generation of Immunity against Pathogens via Single-Domain Antibody-Antigen Constructs." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 12, pp. 4838-4847, (2017) (PubMed).

Görtz, Moshkelgosha, Jesenek, Edelmann, Horstmann, Banga, Eckstein, Berchner-Pfannschmidt: "Pathogenic Phenotype of Adipogenesis and Hyaluronan in Orbital Fibroblasts From Female Graves' Orbitopathy Mouse Model." dans: Endocrinology, Vol. 157, Issue 10, pp. 3771-3778, (2016) (PubMed).

Meng, Li, Geng, Ohe, Yu, E, Ye, Yang, Kato, Zhang, Ishida, Ohta, Jin, Kakehata, Geng, Yamakawa: "Decreased expression of follicular dendritic cell-secreted protein correlates with increased immunoglobulin A production in the tonsils of individuals with immunoglobulin A nephropathy." dans: Translational research : the journal of laboratory and clinical medicine, Vol. 166, Issue 3, pp. 281-91, (2015) (PubMed).

Idriss, Blann, Sayed, Gaber, Hassen, Kishk: "Circulating Endothelial Cells and Platelet Microparticles in Mitral Valve Disease With and Without Atrial Fibrillation." dans: Angiology, Vol. 66, Issue 7, pp. 631-7, (2015) (PubMed).

Young, Tang, Niven-Fairchild, Tadesse, Krikun, Norwitz, Mor, Abrahams, Guller: "Toll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophages." dans: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 73, Issue 1, pp. 22-35, (2014) (PubMed).

Clark: "A Short History of the B-Cell-Associated Surface Molecule CD40." dans: Frontiers in immunology, Vol. 5, pp. 472, (2014) (PubMed).

Lozza, Farinacci, Faé, Bechtle, Stäber, Dorhoi, Bauer, Ganoza, Weber, Kaufmann: "Crosstalk between human DC subsets promotes antibacterial activity and CD8+ T-cell stimulation in response to bacille Calmette-Guérin." dans: European journal of immunology, Vol. 44, Issue 1, pp. 80-92, (2014) (PubMed).

Dibra, Li: "The cell-to-cell coordination between activated T cells and CpG-stimulated macrophages synergistically induce elevated levels of IL-10 via NF-κB1, STAT3, and CD40/CD154." dans: Cell communication and signaling : CCS, Vol. 11, pp. 95, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à CD40

CD40 molecule (CD40), CD40 antigen (Cd40), CD40 molecule (Cd40), AI326936, Bp50, CDW40, GP39, HIGM1, IGM, IMD3, p50, T-BAM, TNFRSF5, Tnfrsf5, TNFSF5, TRAP

Protein level used designations for CD40

  • B cell surface antigen CD40
  • B cell-associated molecule
  • B-cell surface antigen CD40
  • CD40 antigen (TNF receptor superfamily member 5)
  • CD40 type II isoform
  • CD40L receptor
  • nerve growth factor receptor-related B-lymphocyte activation molecule
  • tumor necrosis factor receptor superfamily member 5
  • tumor necrosis factor receptor superfamily, member 5
  • T-cell differentiation antigen
  • human CD40-homologue
  • CD40 antigen, TNF receptor superfamily member 5
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