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CD47 Produits

(CD47)

Catégories

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010].

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Catégories CD47 en vedette

CD47 Anticorps

High quality antibodies with extensive validation data.

CD47 Kits ELISA

Reliable ELISA kits for a wide range of species.

CD47 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CD47 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application FACS, IF, IHC, ELISA, StM, Coat
Validations
  • (6)
N° du produit ABIN6941215
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application FACS, IF, IHC, StM
Validations
  • (6)
N° du produit ABIN6941211
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7439102
Quantité 100 μL
Fiche technique Fiche technique

CD47 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975258
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954524
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954525
Quantité 96 tests
Fiche technique Fiche technique

CD47 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (7)
N° du produit ABIN7274225
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
N° du produit ABIN7274220
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus, Rhesus Monkey
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274217
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CD47

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." dans: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Wang, Sun, Zhou, Chen, Jiao, Li, Gou, Li, Du, Chen, Zhai, Wu, Qi, Gao: "CD47/SIRPα blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy." dans: Journal for immunotherapy of cancer, Vol. 8, Issue 2, (2020) (PubMed).

Wang, Huang, Zhang, Liu, Liang, Jiang, Jiang, Yu, Jiang, Li, Zhang, Wen, Zheng: "Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma." dans: Cancer medicine, Vol. 8, Issue 3, pp. 1315-1325, (2019) (PubMed).

Logtenberg, Jansen, Raaben, Toebes, Franke, Brandsma, Matlung, Fauster, Gomez-Eerland, Bakker, van der Schot, Marijt, Verdoes, Haanen, van den Berg, Neefjes, van den Berg, Brummelkamp, Leusen et al.: "Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy. ..." dans: Nature medicine, Vol. 25, Issue 4, pp. 612-619, (2019) (PubMed).

Josifovska, Szabó, Nagymihály, Veréb, Facskó, Eriksen, Moe, Petrovski: "Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy." dans: Contact lens & anterior eye : the journal of the British Contact Lens Association, Vol. 40, Issue 5, pp. 283-292, (2018) (PubMed).

Ye, Wang, Lu, Zhang, Chen, Zhou: "CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma." dans: Oncology letters, Vol. 15, Issue 6, pp. 9075-9080, (2018) (PubMed).

Davis, Kiss, Trivedi, Metzner, Liao, Gambhir: "Surface-Enhanced Raman Scattering Nanoparticles for Multiplexed Imaging of Bladder Cancer Tissue Permeability and Molecular Phenotype." dans: ACS nano, Vol. 12, Issue 10, pp. 9669-9679, (2018) (PubMed).

Yu, Qiu, Long, Yang, Zhang, Xu, Chang, Du, Hou, Yu, Zeng, Wang, Sun: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." dans: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).

Weiskopf: "Cancer immunotherapy targeting the CD47/SIRPα axis." dans: European journal of cancer (Oxford, England : 1990), Vol. 76, pp. 100-109, (2017) (PubMed).

Kojima, Volkmer, McKenna, Civelek, Lusis, Miller, Direnzo, Nanda, Ye, Connolly, Schadt, Quertermous, Betancur, Maegdefessel, Matic, Hedin, Weissman, Leeper: "CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis." dans: Nature, Vol. 536, Issue 7614, pp. 86-90, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à CD47

alkaline phosphatase, intestinal (ALPI), CD47 molecule (CD47), CD47 antigen (Rh-related antigen, integrin-associated signal transducer) (Cd47), Cd47 molecule (Cd47), 9130415E20Rik, AA407862, AI848868, AW108519, B430305P08Rik, CD47/IAP, IAP, Itgp, MER6, OA3

Protein level used designations for CD47

  • Kasahara isozyme
  • alkaline phosphomonoesterase
  • glycerophosphatase
  • intestinal alkaline phosphatase
  • intestinal-type alkaline phosphatase
  • CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
  • CD47 glycoprotein
  • Rh-related antigen
  • antigen identified by monoclonal antibody 1D8
  • antigenic surface determinant protein OA3
  • integrin associated protein
  • integrin-associated protein
  • integrin-associated signal transducer
  • leukocyte surface antigen CD47
  • IAP
  • CD47 antigen
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