CHRFAM7A Produits
(CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10) and FAM7A (Family with Sequence Similarity 7A, Exons A-E) Fusion (CHRFAM7A))
Catégories
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008].
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Catégories CHRFAM7A en vedette
CHRFAM7A Anticorps
High quality antibodies with extensive validation data.
CHRFAM7A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7147675
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
- (2)
N° du produit
ABIN2776280
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN6098837
Quantité
100 μL
Fiche technique
Fiche technique
CHRFAM7A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6229401
Quantité
96 tests
Fiche technique
Fiche technique
CHRFAM7A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3100532
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CHRFAM7A
: "Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type." dans: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 144B, Issue 5, pp. 611-4, (2007) (PubMed).: "Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway." dans: Cancer research, Vol. 64, Issue 1, pp. 135-45, (2004) (PubMed).
: "Endothelial-leukocyte adhesion molecules in inflammation and metastasis." dans: Thrombosis and haemostasis, Vol. 70, Issue 1, pp. 152-4, (1993) (PubMed).
: "Granular cell basal cell carcinoma. Light microscopy, immunohistochemical and ultrastructural study." dans: Virchows Archiv. A, Pathological anatomy and histopathology, Vol. 422, Issue 2, pp. 173-7, (1993) (PubMed).
: "Expression of selectin ligands by cutaneous squamous cell carcinoma." dans: The American journal of pathology, Vol. 143, Issue 4, pp. 1220-5, (1993) (PubMed).
: "Comparative immunohistochemical study of primary and metastatic carcinomas of the liver." dans: American journal of clinical pathology, Vol. 99, Issue 5, pp. 551-7, (1993) (PubMed).
: "Association of expression of blood group-related carbohydrate antigens with prognosis in breast cancer." dans: Cancer, Vol. 71, Issue 10, pp. 3044-53, (1993) (PubMed).
: "Apocrine carcinoma of the skin. A clinicopathologic, immunocytochemical, and ultrastructural study." dans: Cancer, Vol. 71, Issue 2, pp. 375-81, (1993) (PubMed).
: "Expression of the CD15 antigen in hepatocellular carcinoma." dans: Cancer, Vol. 71, Issue 12, pp. 3864-7, (1993) (PubMed).
: "Adhesive interactions in angiogenesis and metastasis." dans: Pharmacology & therapeutics, Vol. 53, Issue 2, pp. 239-60, (1992) (PubMed).
Synonymes et noms alternatifs relatifs à CHRFAM7A
CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion (CHRFAM7A), CHRNA7, CHRNA7-DR1, D-10Protein level used designations for CHRFAM7A
- CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
- CHRNA7-FAM7A fusion protein
- alpha 7 neuronal nicotinic acetylcholine receptor-FAM7A hybrid
- alpha-7 nicotinic cholinergic receptor subunit
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