CLDN14 Produits
(Claudin 14 (CLDN14))
Catégories
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010].
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Catégories CLDN14 en vedette
CLDN14 Anticorps
High quality antibodies with extensive validation data.
CLDN14 Kits ELISA
Reliable ELISA kits for a wide range of species.
CLDN14 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CLDN14 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7147891
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
- (2)
N° du produit
ABIN1881208
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (3)
N° du produit
ABIN525258
Quantité
100 μL
Fiche technique
Fiche technique
CLDN14 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1742853
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Sheep
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1773757
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1745293
Quantité
96 tests
Fiche technique
Fiche technique
CLDN14 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1349591
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1349593
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3120231
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CLDN14
: "Activation of the Ca(2+)-sensing receptor increases renal claudin-14 expression and urinary Ca(2+) excretion." dans: American journal of physiology. Renal physiology, Vol. 304, Issue 6, pp. F761-9, (2013) (PubMed).: "Identification of transcription factor E3 (TFE3) as a receptor-independent activator of Gα16: gene regulation by nuclear Gα subunit and its activator." dans: The Journal of biological chemistry, Vol. 286, Issue 20, pp. 17766-76, (2011) (PubMed).
: "Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density." dans: Nature genetics, Vol. 41, Issue 8, pp. 926-30, (2009) (PubMed).
: "Mutation in gap and tight junctions in patients with non-syndromic hearing loss." dans: Biochemical and biophysical research communications, Vol. 385, Issue 1, pp. 1-5, (2009) (PubMed).
: "Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29." dans: Cell, Vol. 104, Issue 1, pp. 165-72, (2001) (PubMed).
: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." dans: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
Synonymes et noms alternatifs relatifs à CLDN14
claudin 14 L homeolog (cldn14.L), claudin 14 (CLDN14), claudin 14 (Cldn14), AI851731, claudin-14, CLDN14, DFNB29Protein level used designations for CLDN14
- claudin 14
- claudin-14
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