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CLEC14A Produits

(C-Type Lectin Domain Family 14, Member A (CLEC14A))

Catégories

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012].

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Catégories CLEC14A en vedette

CLEC14A Anticorps

High quality antibodies with extensive validation data.

CLEC14A Kits ELISA

Reliable ELISA kits for a wide range of species.

CLEC14A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CLEC14A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IF (p), IHC (p)
Validations
  • (3)
  • (1)
N° du produit ABIN1385496
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
N° du produit ABIN531111
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
N° du produit ABIN7146053
Quantité 100 μg
Fiche technique Fiche technique

CLEC14A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730716
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4882375
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN6386088
Quantité 96 tests
Fiche technique Fiche technique

CLEC14A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274362
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274351
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122062
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CLEC14A

Kim, Park, Jang, Kim, Na, Lee, Kim, Heo, Yoo, Kim, Lee, Kim, Kim, Kim, Cha, Lee, Lee: "Inhibition of VEGF-dependent angiogenesis and tumor angiogenesis by an optimized antibody targeting CLEC14a." dans: Molecular oncology, Vol. 12, Issue 3, pp. 356-372, (2019) (PubMed).

Botting, Bertram, Baharlou, Sandgren, Fletcher, Rhodes, Rana, Plasto, Wang, Lim, Barnouti, Kohout, Papadopoulos, Merten, Olbourne, Cunningham, Haniffa, Harman: "Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes." dans: Journal of leukocyte biology, Vol. 101, Issue 6, pp. 1393-1403, (2017) (PubMed).

Jang, Kim, Kim, Lee, Kim, Heo, Lee: "CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis." dans: Scientific reports, Vol. 7, Issue 1, pp. 10666, (2017) (PubMed).

Noy, Swain, Khan, Lodhia, Bicknell: "Sprouting angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid-like 2 protein (RHBDL2)." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 6, pp. 2311-23, (2016) (PubMed).

Noy, Lodhia, Khan, Zhuang, Ward, Verissimo, Bacon, Bicknell: "Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth." dans: Oncogene, (2015) (PubMed).

Ki, Jeoung, Choi, Rho, Kwon, Shim, Chung, Hong, Song, Lee: "Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro." dans: Oncogene, Vol. 32, Issue 48, pp. 5449-57, (2013) (PubMed).

Mura, Swain, Zhuang, Vorschmitt, Reynolds, Durant, Beesley, Herbert, Sheldon, Andre, Sanderson, Glen, Luu, McGettrick, Antczak, Falciani, Nash, Nagy, Bicknell: "Identification and angiogenic role of the novel tumor endothelial marker CLEC14A." dans: Oncogene, Vol. 31, Issue 3, pp. 293-305, (2012) (PubMed).

Galvagni, Nardi, Spiga, Trezza, Tarticchio, Pellicani, Andreuzzi, Caldi, Toti, Tosi, Santucci, Iozzo, Mongiat, Orlandini: "Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium." dans: Matrix biology : journal of the International Society for Matrix Biology, Vol. 64, pp. 112-127 (PubMed).

Synonymes et noms alternatifs relatifs à CLEC14A

C-type lectin domain containing 14A (CLEC14A), C-type lectin domain family 14, member a (Clec14a), 1200003C23Rik, AI642649, C14orf27, CEG1, EGFR-5

Protein level used designations for CLEC14A

  • C-type lectin domain family 14 member A
  • ClECT and EGF-like domain containing protein
  • epidermal growth factor receptor 5
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