Complement Factor I Produits
(Complement Factor I (CFI))
Catégories
This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories Complement Factor I en vedette
Complement Factor I Anticorps
High quality antibodies with extensive validation data.
Complement Factor I Kits ELISA
Reliable ELISA kits for a wide range of species.
Complement Factor I Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Complement Factor I recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7444067
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7443707
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
N° du produit
ABIN516816
Quantité
100 μg
Fiche technique
Fiche technique
Complement Factor I recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6955036
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966038
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962758
Quantité
96 tests
Fiche technique
Fiche technique
Complement Factor I recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7274339
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1349215
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3091355
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Complement Factor I
: "A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and Alzheimer's disease." dans: PLoS ONE, Vol. 13, Issue 5, pp. e0195751, (2018) (PubMed).: "Thrombotic microangiopathy without renal involvement: two novel mutations in complement-regulator genes." dans: Journal of thrombosis and haemostasis : JTH, Vol. 14, Issue 2, pp. 340-5, (2016) (PubMed).
: "Atypical hemolytic uremic syndrome: Korean pediatric series." dans: Pediatrics international : official journal of the Japan Pediatric Society, Vol. 57, Issue 3, pp. 431-8, (2015) (PubMed).
: "Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome." dans: Journal of the American Society of Nephrology : JASN, Vol. 16, Issue 7, pp. 2150-5, (2005) (PubMed).
: "Atypical haemolytic uraemic syndrome and mutations in complement regulator genes." dans: Springer seminars in immunopathology, Vol. 27, Issue 3, pp. 359-74, (2005) (PubMed).
: "Enrichment of early fetal-liver hemopoietic stem cells of the rat using monoclonal antibodies against the transferrin receptor, Thy-1, and MRC-OX82." dans: Developmental immunology, Vol. 4, Issue 4, pp. 235-46, (1996) (PubMed).
Synonymes et noms alternatifs relatifs à Complement Factor I
complement factor I S homeolog (cfi.S), complement factor I L homeolog (cfi.L), complement factor I (CFI), complement factor I (cfi), complement component factor i (Cfi), complement factor I (Cfi), ahus3, AHUS3, c3b-ina, C3b-INA, c3bc4bi, c3bina, C3BINA, cfi, Cfi, CFI, factor I, FI, gb:ai721528, IF, kaf, KAF, MGC53615Protein level used designations for Complement Factor I
- complement factor I
- I factor (complement)
- complement factor 1
- C3B/C4B inactivator
- C3b-inactivator
- Konglutinogen-activating factor
- complement component I
- complement control protein factor I
- complement factor I heavy chain
- light chain of factor I
- complement component 1
Avez-vous cherché autre chose?
- Complement Factor H
- Complement Factor Bb
- Complement Factor B
- Complement Component C9b
- Complement C8
- Complement C5b
- Complement C5 Convertase
- Complement C4d
- Complement C4c
- Complement C4
- Complement C3d
- Complement C3c
- Complement C3b
- Complement C3 Convertase
- Complement C2
- Complement C1
- COMP
- COMMD9
- COMMD8
- COMMD7
Vous êtes ici:
