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COPA Produits

(Coatomer Protein Complex, Subunit alpha (COPA))

Catégories

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008].

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Catégories COPA en vedette

COPA Anticorps

High quality antibodies with extensive validation data.

COPA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

COPA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (5)
N° du produit ABIN7266423
Quantité 100 μL
Fiche technique Fiche technique

Application WB, IHC, ICC, IHC (p)
Validations
  • (2)
N° du produit ABIN337288
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
N° du produit ABIN560436
Quantité 50 μL
Fiche technique Fiche technique

COPA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350036
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3091922
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3136483
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits COPA

Watkin, Jessen, Wiszniewski, Vece, Jan, Sha, Thamsen, Santos-Cortez, Lee, Gambin, Forbes, Law, Stray-Pedersen, Cheng, Mace, Anderson, Liu, Tang, Nicholas, Nahmod, Makedonas, Canter, Kwok, Hicks et al.: "COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. ..." dans: Nature genetics, Vol. 47, Issue 6, pp. 654-60, (2015) (PubMed).

Li, Custer, Gilson, Hao, Beattie, Androphy: "α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth." dans: Human molecular genetics, Vol. 24, Issue 25, pp. 7295-307, (2015) (PubMed).

Ting, Wen, Liu, Hsieh-Li, Li, Lin-Chao: "The spinal muscular atrophy disease protein SMN is linked to the Golgi network." dans: PLoS ONE, Vol. 7, Issue 12, pp. e51826, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à COPA

coatomer protein complex subunit alpha (COPA), WD40 repeat-containing protein (copA), coatomer protein complex subunit alpha (cgd8_860), coatomer protein complex subunit alpha (Chro.80105), Coatomer subunit alpha (AFUA_3G08840), coatomer protein complex subunit alpha (copa), coatomer protein complex, subunit alpha (copa), coatomer protein complex subunit alpha (Copa), coatomer protein complex subunit alpha L homeolog (copa.L), AU040324, cb281, COPA, DDBDRAFT_0189693, DDBDRAFT_0233797, DDB_0189693, DDB_0233797, DKFZp469O221, fb13c12, HEP-COP, wu:fb13c12, xenin

Protein level used designations for COPA

  • coatomer protein complex, subunit alpha
  • coatomer protein complex alpha subunit
  • coatomer protein complex subunit alpha
  • Coatomer subunit alpha
  • coatomer subunit alpha
  • alpha-COP
  • alpha-coat protein
  • HEPCOP
  • alpha coat protein
  • proxenin
  • xenin
  • sneezy
  • HEP-COP
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