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Cortactin Protéines

(Cortactin (CTTN))
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010].

12 Résultats

custom-made CTTN Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
N° du produit ABIN7563864
 
custom-made CTTN Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
N° du produit ABIN7555565
 
CTTN Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
N° du produit ABIN1350743
 
CTTN Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
N° du produit ABIN1350741
 
CTTN Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pubmed 5 références
N° du produit ABIN2712518
 
CTTN Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7663389
 
CTTN Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
N° du produit ABIN7576433
 
CTTN Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
N° du produit ABIN7417507
 
CTTN Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
N° du produit ABIN7417462
 
custom-made CTTN Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
N° du produit ABIN3135267
 
custom-made CTTN Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
N° du produit ABIN3095566
 
CTTN Origine: Humain Hôte: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2712519
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
  • Réactivité
    • Human
    • Mouse
    • Rat
  • Cité dans publications
  • Images disponible
  • Carrier free only
  • Hote
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
    • Insect cells (Sf9)
  • Epitope
    • AA 1-509
    • AA 1-546
    • AA 1-550
    • AA 1-208
    • AA 1-513
    • AA 341-450
    • Transcript Variant 2
  • Conjugué
    • His tag
    • GST tag
    • Strep Tag
    • DYKDDDDK Tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Type Proteine
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene

Dernières publications pour nos Cortactin Protéines

Cortés-Vicente, Gallardo, Martínez, Díaz-Manera, Querol, Rojas-García, Illa: "Clinical Characteristics of Patients With Double-Seronegative Myasthenia Gravis and Antibodies to Cortactin." dans: JAMA neurology, Vol. 73, Issue 9, pp. 1099-104, (2016) (PubMed).

Labrador-Horrillo, Martínez, Selva-OCallaghan, Trallero-Araguás, Grau-Junyent, Vilardell-Tarrés, Juarez: "Identification of a novel myositis-associated antibody directed against cortactin." dans: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1008-12, (2014) (PubMed).

Gallardo, Martínez-Hernández, Titulaer, Huijbers, Martínez, Ramos, Querol, Díaz-Manera, Rojas-García, Hayworth, Verschuuren, Balice-Gordon, Dalmau, Illa: "Cortactin autoantibodies in myasthenia gravis." dans: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1003-7, (2014) (PubMed).

Wang, Henry, Distefano, Wang, Räikkönen, Mönkkönen, Tanaka, Morita: "Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human V?2V?2 T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1029-42, (2013) (PubMed).

Llanos, Royer, Lu, Bergamaschi, Lee, Lu: "Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif." dans: The Journal of biological chemistry, Vol. 286, Issue 50, pp. 43039-44, (2011) (PubMed).

Pseudonymes pour Cortactin Protéines

cortactin (CTTN) Protéines
cortactin (Cttn) Protéines
CG3637 gene product from transcript CG3637-RD (Cortactin) Protéines
cortactin S homeolog (cttn.S) Protéines
cortactin L homeolog (cttn.L) Protéines
cortactin (cttn) Protéines
src substrate cortactin (CpipJ_CPIJ006351) Protéines
Src substrate cortactin (Bm1_57220) Protéines
cortactin (LOC100533277) Protéines
1110020L01Rik Protéines
CG3637 Protéines
cortactin Protéines
cttn Protéines
Cttn Protéines
CTTN Protéines
CTTN1 Protéines
Cttnb Protéines
Dmel\CG3637 Protéines
EMS1 Protéines
Ems1 Protéines
ems1 Protéines
P85.25 Protéines
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