Cortactin Produits
(Cortactin (CTTN))
Catégories
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010].
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Catégories Cortactin en vedette
Cortactin Anticorps
High quality antibodies with extensive validation data.
Cortactin Kits ELISA
Reliable ELISA kits for a wide range of species.
Cortactin Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Cortactin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (5)
- (1)
N° du produit
ABIN2854674
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (6)
N° du produit
ABIN6139243
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (7)
N° du produit
ABIN7266511
Quantité
100 μL
Fiche technique
Fiche technique
Cortactin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380549
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380550
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6384450
Quantité
96 tests
Fiche technique
Fiche technique
Cortactin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350741
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350743
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3095566
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Cortactin
: "Clinical Characteristics of Patients With Double-Seronegative Myasthenia Gravis and Antibodies to Cortactin." dans: JAMA neurology, Vol. 73, Issue 9, pp. 1099-104, (2016) (PubMed).: "PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk." dans: Acta neuropathologica, Vol. 130, Issue 5, pp. 731-50, (2015) (PubMed).
: "Identification of a novel myositis-associated antibody directed against cortactin." dans: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1008-12, (2014) (PubMed).
: "Cortactin autoantibodies in myasthenia gravis." dans: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1003-7, (2014) (PubMed).
: "Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human V?2V?2 T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1029-42, (2013) (PubMed).
: "Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif." dans: The Journal of biological chemistry, Vol. 286, Issue 50, pp. 43039-44, (2011) (PubMed).
: "Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases." dans: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3209-23, (2009) (PubMed).
: "Involvement of dynamin-2 in formation of discoid vesicles in urinary bladder umbrella cells." dans: Cell and tissue research, Vol. 337, Issue 1, pp. 91-102, (2009) (PubMed).
: "[Expression and clinical significance of EMS1 gene in gastric carcinoma]." dans: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 3, pp. 323-6, (2008) (PubMed).
: "Association of cortactin, fascin-1 and epidermal growth factor receptor (EGFR) expression in ovarian carcinomas: correlation with clinicopathological parameters." dans: Disease markers, Vol. 25, Issue 1, pp. 17-26, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à Cortactin
cortactin (CTTN), cortactin (Cttn), CG3637 gene product from transcript CG3637-RD (Cortactin), cortactin S homeolog (cttn.S), cortactin L homeolog (cttn.L), cortactin (cttn), src substrate cortactin (CpipJ_CPIJ006351), Src substrate cortactin (Bm1_57220), cortactin (LOC100533277), 1110020L01Rik, CG3637, cortactin, cttn, Cttn, CTTN, CTTN1, Cttnb, Dmel\CG3637, EMS1, Ems1, ems1, P85.25Protein level used designations for Cortactin
- 1110020L01Rik
- amplaxin
- ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate)
- oncogene EMS1
- src substrate cortactin
- mammary tumor and squamous cell carcinoma associated (p80/85 src substrate)
- cortactin isoform B
- CG3637-PA
- CG3637-PB
- CG3637-PC
- CG3637-PD
- Cortactin-PA
- Cortactin-PB
- Cortactin-PC
- Cortactin-PD
- DCortactin
- cortactin
- p80
- p80/85
- src substrate protein p85
- Src substrate cortactin
- src substrate cortactin-like
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