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DDC Produits

(Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Catégories

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011].

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Catégories DDC en vedette

DDC Anticorps

High quality antibodies with extensive validation data.

DDC Kits ELISA

Reliable ELISA kits for a wide range of species.

DDC Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DDC recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (7)
N° du produit ABIN1679510
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p), FACS
Validations
  • (5)
N° du produit ABIN651727
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7436294
Quantité 100 μL
Fiche technique Fiche technique

DDC recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955437
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962232
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6999492
Quantité 96 tests
Fiche technique Fiche technique

DDC recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122700
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN667092
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351264
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits DDC

Koblinger, Jean-Xavier, Sharma, Füzesi, Young, Eaton, Kwok, Bains, Whelan: "Optogenetic Activation of A11 Region Increases Motor Activity." dans: Frontiers in neural circuits, Vol. 12, pp. 86, (2019) (PubMed).

Sharma, Kim, Mayr, Elliott, Whelan: "Parallel descending dopaminergic connectivity of A13 cells to the brainstem locomotor centers." dans: Scientific reports, Vol. 8, Issue 1, pp. 7972, (2018) (PubMed).

Shimohata, Ishihara, Hattori, Miyamoto, Morishita, Ornthanalai, Raveau, Ebrahim, Amano, Yamada, Sago, Akiba, Mataga, Murphy, Miyakawa, Yamakawa: "Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism." dans: Experimental neurology, Vol. 293, pp. 1-12, (2017) (PubMed).

Rivetti di Val Cervo, Romanov, Spigolon, Masini, Martín-Montañez, Toledo, La Manno, Feyder, Pifl, Ng, Sánchez, Linnarsson, Wernig, Harkany, Fisone, Arenas: "Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model." dans: Nature biotechnology, Vol. 35, Issue 5, pp. 444-452, (2017) (PubMed).

Jang, Park, Lee, Lee, Kim, Koh: "1,25-dyhydroxyvitamin D3 attenuates L-DOPA-induced neurotoxicity in neural stem cells." dans: Molecular neurobiology, Vol. 51, Issue 2, pp. 558-70, (2015) (PubMed).

Hiramoto, Yamate, Kawanishi: "Detection of Dopa-positive cells in mouse ovaries in response to ocular exposure to ultraviolet B rays." dans: Photodermatology, photoimmunology & photomedicine, (2014) (PubMed).

Koblinger, Füzesi, Ejdrygiewicz, Krajacic, Bains, Whelan: "Characterization of A11 neurons projecting to the spinal cord of mice." dans: PLoS ONE, Vol. 9, Issue 10, pp. e109636, (2014) (PubMed).

San Sebastian, Kells, Bringas, Samaranch, Hadaczek, Ciesielska, Macayan, Pivirotto, Forsayeth, Osborne, Wright, Green, Heller, Bankiewicz: "SAFETY AND TOLERABILITY OF MRI-GUIDED INFUSION OF AAV2-hAADC INTO THE MID-BRAIN OF NON-HUMAN PRIMATE." dans: Molecular therapy. Methods & clinical development, Vol. 3, (2014) (PubMed).

Blechingberg, Holm, Johansen, Børglum, Nielsen: "Aromatic l-amino acid decarboxylase expression profiling and isoform detection in the developing porcine brain." dans: Brain research, Vol. 1308, pp. 1-13, (2009) (PubMed).

Voeller: "Attention-deficit hyperactivity disorder (ADHD)." dans: Journal of child neurology, Vol. 19, Issue 10, pp. 798-814, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à DDC

dopa decarboxylase (DDC), dopa decarboxylase (ddc), dopa decarboxylase (Ddc), Dopa-decarboxylase (Dvir\Ddc), dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), Dopa decarboxylase (Ddc), dopa decarboxylase L homeolog (ddc.L), 5-HT, AADC, Aadc, CG10697, Ddc, DDC, ddc, DdcDm, DdcDv, Dmel\\CG10697, Dvir\\GJ17995, dvir_GLEANR_2561, fDDC, GJ17995, l(2)37Bl, l(2)37Ch, l(2)k02104, wu:fa56d05, wu:fd59h03, wu:fk20h01, zgc:65801, zgc:76929

Protein level used designations for DDC

  • aromatic-L-amino-acid decarboxylase
  • L-aromatic dopa decarboxylase
  • aromatic-L-amino acid decarboxylase
  • aromatic amino acid decarboxylase
  • Ddc-PA
  • Dvir\\Ddc-PA
  • Dvir\\GJ17995-PA
  • GJ17995-PA
  • L-Dopa decarboxylase
  • AADC
  • aromatic L-amino acid decarboxylase
  • 3,4-Dihydroxyphenylalanine decarboxylase
  • CG10697-PB
  • CG10697-PC
  • CG10697-PD
  • Ddc-PB
  • Ddc-PC
  • Ddc-PD
  • dopa decarboxylase
  • dopa-decarboxylase
  • dopadecarboxylase
  • dopamine decarboxylase
  • transcription unit No. 3
  • dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Aromatic-L-amino-acid decarboxylase
  • aromatic-L-amino-acid decarboxylase-like
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