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desert Hedgehog Produits

(Desert Hedgehog (DHH))

Catégories

This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved\; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010].

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Catégories desert Hedgehog en vedette

desert Hedgehog Anticorps

High quality antibodies with extensive validation data.

desert Hedgehog Kits ELISA

Reliable ELISA kits for a wide range of species.

desert Hedgehog Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

desert Hedgehog recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7438166
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7437344
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7190469
Quantité 100 μL
Fiche technique Fiche technique

desert Hedgehog recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955358
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6974699
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966339
Quantité 96 tests
Fiche technique Fiche technique

desert Hedgehog recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN5509480
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122645
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122644
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits desert Hedgehog

Wellbrock, Latuske, Köhler, Wagner, Stamm, Vettorazzi, Vohwinkel, Klokow, Uibeleisen, Ehm, Riecken, Loges, Thol, Schubert, Amling, Jücker, Bokemeyer, Heuser, Krauter, Fiedler: "Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 10, pp. 2388-98, (2016) (PubMed).

Bashir, Halepoto, Al-Ayadhi: "Serum level of desert hedgehog protein in autism spectrum disorder: preliminary results." dans: Medical principles and practice : international journal of the Kuwait University, Health Science Centre, Vol. 23, Issue 1, pp. 14-7, (2014) (PubMed).

Callier, Calvel, Matevossian, Makrythanasis, Bernard, Kurosaka, Vannier, Thauvin-Robinet, Borel, Mazaud-Guittot, Rolland, Desdoits-Lethimonier, Guipponi, Zimmermann, Stévant, Kuhne, Conne, Santoni et al.: "Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling. ..." dans: PLoS genetics, Vol. 10, Issue 5, pp. e1004340, (2014) (PubMed).

McKee, Xu, Cao, Kabraji, Allen, Kersemans, Beech, Smart, Hamdy, Ishkanian, Sykes, Pintile, Milosevic, van der Kwast, Zafarana, Ramnarine, Jurisica, Mallof, Lam, Bristow, Muschel: "Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma." dans: The Journal of clinical investigation, Vol. 122, Issue 11, pp. 4025-36, (2012) (PubMed).

Nishimori, Ehata, Suzuki, Katsuno, Miyazono: "Prostate cancer cells and bone stromal cells mutually interact with each other through bone morphogenetic protein-mediated signals." dans: The Journal of biological chemistry, Vol. 287, Issue 24, pp. 20037-46, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à desert Hedgehog

desert hedgehog (DHH), desert hedgehog (dhh), desert hedgehog (Dhh), desert hedgehog L homeolog (dhh.L), desert hedgehog S homeolog (dhh.S), C78960, chh, chh-a, dhh, dhh-1, dhh-A, GDXYM, hh4, HHG-3, SRXY7, x-chh, Xchh

Protein level used designations for desert Hedgehog

  • desert hedgehog homolog
  • desert hedgehog protein
  • mutant desert hedgehog
  • HHG-3
  • desert hedgehog
  • DHH-1
  • X-CHH
  • cephalic hedgehog protein
  • desert hedgehog protein 1
  • desert hedgehog protein A
  • DHH-2
  • X-HH4
  • cephalic hedgehog
  • desert hedgehog homolog, hedgehog protein 4
  • desert hedgehog protein 2
  • desert hedgehog protein B
  • hedgehog protein 4
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