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DGCR8 Produits

(DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Catégories

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010].

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Catégories DGCR8 en vedette

DGCR8 Anticorps

High quality antibodies with extensive validation data.

DGCR8 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DGCR8 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (4)
N° du produit ABIN527085
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IP, IF
Validations
  • (5)
N° du produit ABIN950085
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (5)
N° du produit ABIN527086
Quantité 100 μg
Fiche technique Fiche technique

DGCR8 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6203730
Quantité 96 tests
Fiche technique Fiche technique

DGCR8 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351506
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351505
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3092171
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits DGCR8

Belair, Paikari, Moltzahn, Shenoy, Yau, DallEra, Simko, Benz, Blelloch: "DGCR8 is essential for tumor progression following PTEN loss in the prostate." dans: EMBO reports, Vol. 16, Issue 9, pp. 1219-32, (2015) (PubMed).

Márquez, Kohli, Arteta, Chang, Li, Goldblatt, Vidal-Vanaclocha: "Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation." dans: International journal of cancer. Journal international du cancer, Vol. 133, Issue 9, pp. 2113-22, (2013) (PubMed).

Van Duyne, Guendel, Klase, Narayanan, Coley, Jaworski, Roman, Popratiloff, Mahieux, Kehn-Hall, Kashanchi: "Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery." dans: PLoS ONE, Vol. 7, Issue 7, pp. e40662, (2012) (PubMed).

Havens, Reich, Duelli, Hastings: "Biogenesis of mammalian microRNAs by a non-canonical processing pathway." dans: Nucleic acids research, Vol. 40, Issue 10, pp. 4626-40, (2012) (PubMed).

Kye, Neveu, Lee, Zhou, Steen, Sahin, Kosik, Silva: "NMDA mediated contextual conditioning changes miRNA expression." dans: PLoS ONE, Vol. 6, Issue 9, pp. e24682, (2011) (PubMed).

Luers, Loudig, Berman: "MicroRNAs are expressed and processed by human primary macrophages." dans: Cellular immunology, Vol. 263, Issue 1, pp. 1-8, (2010) (PubMed).

Smith, Shah, Cidlowski: "Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis." dans: The Journal of biological chemistry, Vol. 285, Issue 47, pp. 36698-708, (2010) (PubMed).

Yeom, Lee, Han, Suh, Kim: "Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing." dans: Nucleic acids research, Vol. 34, Issue 16, pp. 4622-9, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à DGCR8

DGCR8 microprocessor complex subunit L homeolog (dgcr8.L), DiGeorge syndrome critical region gene 8 (DGCR8), DGCR8 microprocessor complex subunit (dgcr8), DGCR8, microprocessor complex subunit (DGCR8), DGCR8, microprocessor complex subunit (Dgcr8), DGCR8 microprocessor complex subunit (Dgcr8), microRNA 3618 (MIR3618), C22orf12, D16H22S788E, D16H22S1742E, D16Wis2, DGCR8, dgcrk6, DGCRK6, gy1, Gy1, MGC78846, N41, pasha, si:ch211-106a19.4, Vo59c07, wu:fc23f08, wu:fc38f06

Protein level used designations for DGCR8

  • hypothetical protein LOC432110
  • DiGeorge syndrome critical region gene 8
  • DiGeorge syndrome critical region 8
  • microprocessor complex subunit DGCR8
  • diGeorge syndrome critical region 8 homolog
  • DiGeorge syndrome critical region 8 homolog
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