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DUSP12 Protéines

(Dual Specificity Phosphatase 12 (DUSP12))

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008].

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DUSP12 Protein (AA 1-340) (His tag)

custom-made DUSP12 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant DUSP12 Protein, UniprotID Q9UNI6

3 images

N° du produit ABIN7547264

Détails

DUSP12 Protein (AA 1-339) (His tag)

custom-made DUSP12 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Dusp12 Protein, UniprotID Q9D0T2

3 images

N° du produit ABIN7560853

Détails

DUSP12 Protein (AA 1-340) (GST tag)

DUSP12 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP

Image no. 1 for Dual Specificity Phosphatase 12 (DUSP12) (AA 1-340) protein (GST tag) (ABIN1352104)

1 image

N° du produit ABIN1352104

Détails

DUSP12 Protein (AA 1-339) (Strep Tag)

custom-made DUSP12 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3128827

Détails

DUSP12 Protein (AA 1-340) (Strep Tag)

custom-made DUSP12 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3079207