DUSP12 Produits
(Dual Specificity Phosphatase 12 (DUSP12))
Catégories
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008].
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Catégories DUSP12 en vedette
DUSP12 Anticorps
High quality antibodies with extensive validation data.
DUSP12 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DUSP12 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IP, IF
Validations
- (3)
N° du produit
ABIN524689
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (2)
N° du produit
ABIN524688
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
N° du produit
ABIN1537912
Quantité
400 μL
Fiche technique
Fiche technique
DUSP12 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352104
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3079207
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3128827
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits DUSP12
: "Dual-specificity phosphatases: critical regulators with diverse cellular targets." dans: The Biochemical journal, Vol. 418, Issue 3, pp. 475-89, (2009) (PubMed).: "Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses." dans: Nature reviews. Drug discovery, Vol. 6, Issue 5, pp. 391-403, (2007) (PubMed).
: "Characterization of rat LECAM-1 (L-selectin) by the use of monoclonal antibodies and evidence for the presence of soluble LECAM-1 in rat sera." dans: European journal of immunology, Vol. 23, Issue 9, pp. 2181-8, (1993) (PubMed).
Synonymes et noms alternatifs relatifs à DUSP12
dual specificity phosphatase 12 (DUSP12), dual specificity phosphatase 12 (dusp12), dual specificity phosphatase 12 L homeolog (dusp12.L), Dual specificity protein phosphatase 12 (GL50803_36315), dual specificity protein phosphatase 12 (MGYG_01770), dual specificity phosphatase 12 (Dusp12), 1190004O14Rik, AA027408, AW049275, DUSP1, DUSP12, dusp12, ESTM36, GKAP, LMW-DSP4, MGC154526, mVH1, T-DSP4, VH1, YVH1, zgc:114069Protein level used designations for DUSP12
- dual specificity phosphatase 12
- dual specificity protein phosphatase 12
- Dual specificity protein phosphatase 12
- dual specificity protein phosphatase 12-like
- YVH1 protein-tyrosine phosphatase ortholog
- dual specificity tyrosine phosphatase YVH1
- serine/threonine specific protein phosphatase
- dual specificity phosphatase T-DSP4
- dual specificity phosphatase VH1
- glucokinase-associated dual specificity phosphatase
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