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EGFR Produits

(Epidermal Growth Factor Receptor (EGFR))

Catégories

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

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Catégories EGFR en vedette

EGFR Anticorps

High quality antibodies with extensive validation data.

EGFR Kits ELISA

Reliable ELISA kits for a wide range of species.

EGFR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

EGFR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (3)
  • (2)
  • (1)
N° du produit ABIN98862
Quantité 250 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (7)
N° du produit ABIN1724824
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7426025
Quantité 100 μL
Fiche technique Fiche technique

EGFR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN837930
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Cell ELISA
Validations
  • (4)
  • (5)
N° du produit ABIN1981827
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Cell ELISA
Validations
  • (4)
  • (5)
N° du produit ABIN1981825
Quantité 96 tests
Fiche technique Fiche technique

EGFR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274526
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274527
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274524
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits EGFR

Haueis, Stech, Kubick: "A Cell-free Expression Pipeline for the Generation and Functional Characterization of Nanobodies." dans: Frontiers in bioengineering and biotechnology, Vol. 10, pp. 896763, (2022) (PubMed).

Lanzerstorfer, Müller, Gordiyenko, Weghuber, Niemeyer: "Highly Modular Protein Micropatterning Sheds Light on the Role of Clathrin-Mediated Endocytosis for the Quantitative Analysis of Protein-Protein Interactions in Live Cells." dans: Biomolecules, Vol. 10, Issue 4, (2021) (PubMed).

Saveri, De Luca, Nisi, Pisciotta, Romano, Piscosquito, Reilly, Polke, Cavallaro, Fabrizi, Fossa, Cichero, Lombardi, Lauria, Magri, Taroni, Pareyson, Bucci: "Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation." dans: Cells, Vol. 9, Issue 4, (2020) (PubMed).

Larios, Mercier, Roux, Gruenberg: "ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes." dans: The Journal of cell biology, Vol. 219, Issue 3, (2020) (PubMed).

Murakami, Matsumoto, Kanamori: "Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system." dans: Scientific reports, Vol. 9, Issue 1, pp. 671, (2020) (PubMed).

El-Sharief, Ammar, Belal, El-Sharief, Mohamed, Mehany, Elhag Ali, Ragab: "Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers." dans: Bioorganic chemistry, Vol. 85, pp. 399-412, (2020) (PubMed).

Al-Harbi, El-Sharief, Abbas: "Synthesis and anticancer activity of bis-benzo[d][1,3]dioxol-5-yl thiourea derivatives with molecular docking study." dans: Bioorganic chemistry, Vol. 90, pp. 103088, (2020) (PubMed).

Tang, Zheng, Melo, Mabardi, Castaño, Xie, Li, Kudchodkar, Wong, Jeng, Maus, Irvine: "Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery." dans: Nature biotechnology, Vol. 36, Issue 8, pp. 707-716, (2019) (PubMed).

Mortensen, Skovsgaard, Okholm, Scavenius, Dupont, Rosen, Enghild, Kjems, Gothelf: "Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins." dans: Bioconjugate chemistry, Vol. 29, Issue 9, pp. 3016-3025, (2019) (PubMed).

Hu, Wang, Jin, Liu, Cui, Sun, Li, Li, Wang, Zhen, Miao, Li: "An EGFR-targeting antibody-drug conjugate LR004-VC-MMAE: potential in esophageal squamous cell carcinoma and other malignancies." dans: Molecular oncology, Vol. 13, Issue 2, pp. 246-263, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à EGFR

epidermal growth factor receptor (EGFR), Epidermal growth factor receptor (Egfr), epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra), epidermal growth factor receptor (egfr1), epidermal growth factor receptor (LOC5564544), epidermal growth factor receptor (Egfr), 9030024J15Rik, AI552599, C-erb, c-erbB, CG10079, D-Egf, d-egf-r, D-EGFR, DEGFR, DEgfr, Degfr, dEGFR, dEgfr, dEGFR1, DER, Der, der, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DER flb, Dmel\\CG10079, DmHD-33, EFG-R, Egf, EGF-R, Egf-r, EGFR, EGFr, EGfr, EgfR, egfr, egfr1, EGFR12, EGFR15, EK2-6, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, ERBB, Erbb, ErbB-1, ERBB1, Erbb2, Errb1, Errp, flb, HD-33, HER1, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57Ea, l(2)57EFa, mENA, mor1, PIG61, TOP, top, top/DER, top/flb, Torpedo/DER, Torpedo/Egfr, torpedo/Egfr, torpedo/egfr, wa-2, wa2, Wa5

Protein level used designations for EGFR

  • CG10079-PA
  • CG10079-PB
  • DER-Ellipse
  • EGF-receptor
  • EGFR
  • Egf receptor
  • Egfr-PA
  • Egfr-PB
  • drosophila epidermal growth factor receptor homologue
  • ellipse
  • ellipse torpedo
  • epidermal growth factor receptor
  • faint little ball
  • morphological defects 1
  • torpedo
  • torpedo/DER
  • erbb1a
  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
  • cell growth inhibiting protein 40
  • cell proliferation-inducing protein 61
  • proto-oncogene c-ErbB-1
  • receptor tyrosine-protein kinase erbB-1
  • EGFR-related peptide
  • Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1)
  • avian erythroblastic leukemia viral (v-erbB) oncogene homolog
  • epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1)
  • waved 2
  • CER
  • epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • egf receptor
  • receptor tyrosine kinase ErbB1
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