EGLN1 Produits
(Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
Catégories
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009].
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Catégories EGLN1 en vedette
EGLN1 Anticorps
High quality antibodies with extensive validation data.
EGLN1 Kits ELISA
Reliable ELISA kits for a wide range of species.
EGLN1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
EGLN1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (6)
N° du produit
ABIN3021560
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
N° du produit
ABIN7266909
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (5)
N° du produit
ABIN7255273
Quantité
200 μL
Fiche technique
Fiche technique
EGLN1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955511
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955510
Quantité
96 tests
Fiche technique
Fiche technique
EGLN1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352445
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352443
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3092287
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits EGLN1
: "Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis. ..." dans: Nature communications, Vol. 9, Issue 1, pp. 5426, (2019) (PubMed).: "Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. ..." dans: Nature communications, Vol. 10, Issue 1, pp. 903, (2019) (PubMed).
: "Metallothionein 3 Controls the Phenotype and Metabolic Programming of Alternatively Activated Macrophages." dans: Cell reports, Vol. 27, Issue 13, pp. 3873-3886.e7, (2019) (PubMed).
: "A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension." dans: Nature communications, Vol. 10, Issue 1, pp. 2130, (2019) (PubMed).
: "Systemic silencing of PHD2 causes reversible immune regulatory dysfunction. ..." dans: The Journal of clinical investigation, Vol. 130, pp. 3640-3656, (2019) (PubMed).
: "The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia." dans: Cell metabolism, Vol. 27, Issue 4, pp. 898-913.e7, (2018) (PubMed).
: "Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat." dans: Anatolian journal of cardiology, Vol. 19, Issue 4, pp. 259-266, (2018) (PubMed).
: "Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen." dans: Nature communications, Vol. 9, Issue 1, pp. 4545, (2018) (PubMed).
: "The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels." dans: eLife, Vol. 6, (2017) (PubMed).
: "Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice." dans: Journal of cellular and molecular medicine, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à EGLN1
egl nine homolog 1 (C. elegans) (EGLN1), egl-9 family hypoxia inducible factor 1 (EGLN1), egl-9 family hypoxia-inducible factor 1 S homeolog (egln1.S), egl-9 family hypoxia-inducible factor 1b (egln1b), egl-9 family hypoxia-inducible factor 1 (Egln1), AI503754, C1orf12, ECYT3, EGLN1, egln2, Hif-p4h-2, HIF-PH2, HIFPH2, HPH-2, HPH2, ORF13, PHD-2, phd2, Phd2, PHD2, SM-20, SM20, zgc:92314, ZMYND6Protein level used designations for EGLN1
- egl nine homolog 1 (C. elegans)
- egl nine homolog 1
- egl nine homolog 1-like
- egl nine homolog 2
- Hif-p4h-2
- HIF-prolyl hydroxylase 2
- hypoxia-inducible factor prolyl hydroxylase 2
- prolyl hydroxylase domain-containing protein 2
- HIF prolyl hydroxylase 2
- egl nine-like protein 1
- zinc finger MYND domain-containing protein 6
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