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EGFR Protéines

(Epidermal Growth Factor Receptor (EGFR))
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

67 Résultats

EGFR Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274526
 
EGFR Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274527
 
EGFR Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Pubmed 1 reference
N° du produit ABIN2181000
 
EGFR Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Pubmed 3 références
N° du produit ABIN5674594
 
EGFR Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Pubmed 1 reference
N° du produit ABIN4949022
 
EGFR Origine: Macaque rhésus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274521
 
EGFR Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Pubmed 1 reference
N° du produit ABIN1352437
 
EGFR Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
N° du produit ABIN6964078
 
EGFR Origine: Cynomolgus Hôte: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7538225
 
EGFR Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7122802
 
EGFR Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
N° du produit ABIN1352441
 
EGFR Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE. Active
N° du produit ABIN7317119
 
EGFR Origine: Rat Hôte: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
N° du produit ABIN7321215
 
EGFR Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
N° du produit ABIN7320051
 
EGFR Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
N° du produit ABIN7320052
 
EGFR Origine: Souris Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7491123
 
EGFR Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274528
 
EGFR Origine: Humain Hôte: CHO Cells Recombinant > 90% by SDS-PAGE SDS
N° du produit ABIN7281111
 
EGFR Origine: Macaque rhésus Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN2870847
 
EGFR Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
N° du produit ABIN4949096
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Antibody Production (AbP)
    • Positive Control (PC)
    • Standard (STD)
    • Functional Studies (Func)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Mass Spectrometry (MS)
    • Activity Assay (AcA)
    • Biochemical Assay (BCA)
    • Kinase Activity Assay (KAA)
  • Réactivité
    • Human
    • Mouse
    • Rhesus Monkey
    • Rat
    • Cynomolgus
    • Rabbit
  • Cité dans publications
  • Images disponible
  • Carrier free only
  • Hote
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Human Cells
    • Insect cells (Sf9)
    • CHO Cells
    • Insect Cells
    • Mammalian Cells
    • Wheat germ
    • Baculovirus
    • Baculovirus infected Insect Cells
    • Yeast
  • Epitope
    • AA 25-645
    • AA 25-378
    • Soluble
    • partial
    • AA 204-370
    • AA 25-30
    • AA 25-647
    • AA 298-645
    • Mutant
    • Transcript Variant 3
    • AA 1-405
    • AA 1-640
    • AA 1-85
    • AA 1025-1210
    • AA 25-389
    • AA 26-645
    • AA 301-645
    • AA 319-484
    • AA 668-1210
    • AA 669-1210
    • AA 672-1210
    • AA 713-984
    • AA 888-1210
    • GST-His-Tag
    • Isoform 1
    • Monomer
    • glycosylated
  • Conjugué
    • His tag
    • Fc Tag
    • Inconjugué
    • GST tag
    • Strep Tag
    • His tag,AVI tag,Biotin
    • APC,His tag
    • DYKDDDDK Tag
    • DYKDDDDK-His Tag
    • FITC,Fc Tag
    • FITC,His tag
    • FITC,His-Avi Tag
    • Fc Tag,His tag
    • Fc-Avi Tag,Biotin
    • GST tag,His tag
    • GST-His-Tag
    • His tag,AVI tag
    • His-Avi Tag
    • His-Avi Tag,Biotin
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
    • PE,His tag
    • hIgG-His-tag
  • Type Proteine
    • Recombinant
    • Native
  • Format
    • Lyophilized
    • Liquid
    • Frozen
  • Activité biologique
    • Biologically Active
    • Biologically Inactive
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • OriGene
    • ProSci
    • CUSABIO
    • Cohesion Biosciences
    • Abbexa
    • Active Motif
    • ITSI-Biosciences

Dernières publications pour nos EGFR Protéines

Haueis, Stech, Kubick: "A Cell-free Expression Pipeline for the Generation and Functional Characterization of Nanobodies." dans: Frontiers in bioengineering and biotechnology, Vol. 10, pp. 896763, (2022) (PubMed).

Murakami, Matsumoto, Kanamori: "Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system." dans: Scientific reports, Vol. 9, Issue 1, pp. 671, (2020) (PubMed).

Tang, Zheng, Melo, Mabardi, Castaño, Xie, Li, Kudchodkar, Wong, Jeng, Maus, Irvine: "Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery." dans: Nature biotechnology, Vol. 36, Issue 8, pp. 707-716, (2019) (PubMed).

Mortensen, Skovsgaard, Okholm, Scavenius, Dupont, Rosen, Enghild, Kjems, Gothelf: "Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins." dans: Bioconjugate chemistry, Vol. 29, Issue 9, pp. 3016-3025, (2019) (PubMed).

Hu, Wang, Jin, Liu, Cui, Sun, Li, Li, Wang, Zhen, Miao, Li: "An EGFR-targeting antibody-drug conjugate LR004-VC-MMAE: potential in esophageal squamous cell carcinoma and other malignancies." dans: Molecular oncology, Vol. 13, Issue 2, pp. 246-263, (2019) (PubMed).

Choi, Yu, Castano, Bouffard, Schmidts, Larson, Bailey, Boroughs, Frigault, Leick, Scarfò, Cetrulo, Demehri, Nahed, Cahill, Wakimoto, Curry, Carter, Maus: "CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity." dans: Nature biotechnology, (2019) (PubMed).

Minkoff, Blatz, Choudhury, Benjamin, Shohet, Sussman: "Plasma-Generated OH Radical Production for Analyzing Three-Dimensional Structure in Protein Therapeutics." dans: Scientific reports, Vol. 7, Issue 1, pp. 12946, (2019) (PubMed).

Kahl, Settele, Knick, Haupts, Bosse-Doenecke: "Mabfilin and Fabfilin - New antibody-scaffold fusion formats for multispecific targeting concepts." dans: Protein expression and purification, Vol. 149, pp. 51-65, (2018) (PubMed).

Fazekas-Singer, Singer, Ilieva, Matz, Herrmann, Spillner, Karagiannis, Jensen-Jarolim: "AllergoOncology: Generating a canine anticancer IgE against the epidermal growth factor receptor." dans: The Journal of allergy and clinical immunology, Vol. 142, Issue 3, pp. 973-976.e11, (2018) (PubMed).

Alvarez-Cienfuegos, Nuñez-Prado, Compte, Cuesta, Blanco-Toribio, Harwood, Villate, Merino, Bonet, Navarro, Muñoz-Briones, Sørensen, Mølgaard, Oliva, Sanz, Blanco, Alvarez-Vallina: "Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains." dans: Scientific reports, Vol. 6, pp. 28643, (2018) (PubMed).

Pseudonymes pour EGFR Protéines

epidermal growth factor receptor (EGFR) Protéines
Epidermal growth factor receptor (Egfr) Protéines
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra) Protéines
epidermal growth factor receptor (egfr1) Protéines
epidermal growth factor receptor (LOC5564544) Protéines
epidermal growth factor receptor (Egfr) Protéines
9030024J15Rik Protéines
AI552599 Protéines
C-erb Protéines
c-erbB Protéines
CG10079 Protéines
D-Egf Protéines
d-egf-r Protéines
D-EGFR Protéines
DEGFR Protéines
DEgfr Protéines
Degfr Protéines
dEGFR Protéines
dEgfr Protéines
dEGFR1 Protéines
DER Protéines
Der Protéines
der Protéines
DER/EGFR Protéines
DER/faint little ball Protéines
DER/top Protéines
DER/torpedo Protéines
DER1 Protéines
DER flb Protéines
Dmel\\CG10079 Protéines
DmHD-33 Protéines
EFG-R Protéines
Egf Protéines
EGF-R Protéines
Egf-r Protéines
EGFR Protéines
EGFr Protéines
EGfr Protéines
EgfR Protéines
egfr Protéines
egfr1 Protéines
EGFR12 Protéines
EGFR15 Protéines
EK2-6 Protéines
El Protéines
Elp Protéines
Elp-1 Protéines
Elp-B1 Protéines
Elp-B1RB1 Protéines
ERBB Protéines
Erbb Protéines
ErbB-1 Protéines
ERBB1 Protéines
Erbb2 Protéines
Errb1 Protéines
Errp Protéines
flb Protéines
HD-33 Protéines
HER1 Protéines
l(2)05351 Protéines
l(2)09261 Protéines
l(2)57DEFa Protéines
l(2)57Ea Protéines
l(2)57EFa Protéines
mENA Protéines
mor1 Protéines
PIG61 Protéines
TOP Protéines
top Protéines
top/DER Protéines
top/flb Protéines
Torpedo/DER Protéines
Torpedo/Egfr Protéines
torpedo/Egfr Protéines
torpedo/egfr Protéines
wa-2 Protéines
wa2 Protéines
Wa5 Protéines
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