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EP400 Produits

(E1A Binding Protein P400 (EP400))

Catégories

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400 (By similarity). Regulates transcriptional activity of ZNF42.

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Catégories EP400 en vedette

EP400 Anticorps

High quality antibodies with extensive validation data.

EP400 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
N° du produit ABIN528254
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (2)
N° du produit ABIN528253
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN6140195
Quantité 100 μL
Fiche technique Fiche technique

EP400 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1352867
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits EP400

Obri, Ouararhni, Papin, Diebold, Padmanabhan, Marek, Stoll, Roy, Reilly, Mak, Dimitrov, Romier, Hamiche: "ANP32E is a histone chaperone that removes H2A.Z from chromatin." dans: Nature, Vol. 505, Issue 7485, pp. 648-53, (2014) (PubMed).

Krukenberg, Jiang, Steen, Mitchison: "Basal activity of a PARP1-NuA4 complex varies dramatically across cancer cell lines." dans: Cell reports, Vol. 8, Issue 6, pp. 1808-18, (2014) (PubMed).

Illingworth, Botting, Grimes, Bickmore, Eskeland: "PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells." dans: PLoS ONE, Vol. 7, Issue 4, pp. e34848, (2012) (PubMed).

Iwai, Takegami, Shiozaki, Miyazaki: "Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP." dans: PLoS ONE, Vol. 6, Issue 6, pp. e20718, (2011) (PubMed).

Smith, White, Sowa, Powell, Ottinger, Harper, Howley: "Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 8, pp. 3752-7, (2010) (PubMed).

Powell, Smith, Sowa, Harper, Iftner, Stubenrauch, Howley: "NCoR1 mediates papillomavirus E8;E2C transcriptional repression." dans: Journal of virology, Vol. 84, Issue 9, pp. 4451-60, (2010) (PubMed).

Xu, Sun, Jiang, Ayrapetov, Moskwa, Yang, Weinstock, Price: "The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair." dans: The Journal of cell biology, Vol. 191, Issue 1, pp. 31-43, (2010) (PubMed).

Young, Schlisio, Minamishima, Zhang, Li, Grisanzio, Signoretti, Kaelin: "VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400." dans: Nature cell biology, Vol. 10, Issue 3, pp. 361-9, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à EP400

E1A binding protein p400 (EP400), E1A binding protein p400 (Ep400), EP400 N-terminal-like protein (LOC738562), helicase domino (LOC5570719), E1a binding protein P400 (CpipJ_CPIJ007689), E1a binding protein P400 (CpipJ_CPIJ007688), E1a binding protein P400 (CpipJ_CPIJ007686), E1a binding protein P400 (CpipJ_CPIJ008061), 1700020J09Rik, AU023439, CAGH32, mDomino, mKIAA1498, P400, p400, TNRC12

Protein level used designations for EP400

  • CAG repeat protein 32
  • E1A-binding protein p400
  • domino homolog
  • hDomino
  • p400 SWI2/SNF2-related protein
  • p400 kDa SWI2/SNF2-related protein
  • trinucleotide repeat containing 12
  • trinucleotide repeat-containing gene 12 protein
  • E1A binding protein p400
  • E1a binding protein P400
  • e1A-binding protein p400-like
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