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EPAS1 Produits

(Endothelial PAS Domain Protein 1 (EPAS1))

Catégories

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009].

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Catégories EPAS1 en vedette

EPAS1 Anticorps

High quality antibodies with extensive validation data.

EPAS1 Kits ELISA

Reliable ELISA kits for a wide range of species.

EPAS1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

EPAS1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7435523
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7435526
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (6)
N° du produit ABIN3187839
Quantité 100 μL
Fiche technique Fiche technique

EPAS1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955560
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955561
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955559
Quantité 96 tests
Fiche technique Fiche technique

EPAS1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1778132
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1352872
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3092376
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits EPAS1

Eroglu, Kocyiğit, Karakukcu, Tuncay, Zararsiz, Eren, Kahriman, Hayri Sipahioglu, Tokgoz, Tasdemir, Oymak: "Hypoxia-inducible factors in arteriovenous fistula maturation: A prospective cohort study." dans: European journal of clinical investigation, Vol. 50, Issue 12, pp. e13350, (2020) (PubMed).

Kong, Oh, Lim, Kim, Han, Choi, Kwon, Nam, Park, Park, Han, Yoo, Lee, Kim, Kang, Choi, Eremina, Quaggin, Ryu, Kang: "Selective tubular activation of hypoxia-inducible factor-2α has dual effects on renal fibrosis." dans: Scientific reports, Vol. 7, Issue 1, pp. 11351, (2019) (PubMed).

Thompson, Alvarez, Singha, Pavesic, Nguyen, Nelson, Fruman, Razorenova: "Targeting the Mevalonate Pathway Suppresses VHL-Deficient CC-RCC through an HIF-Dependent Mechanism." dans: Molecular cancer therapeutics, Vol. 17, Issue 8, pp. 1781-1792, (2019) (PubMed).

Karagiota, Kourti, Simos, Mylonis: "HIF-1α-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia." dans: Cellular and molecular life sciences : CMLS, Vol. 76, Issue 4, pp. 809-825, (2019) (PubMed).

Krueger, Catanese, Sciesielski, Kirschner, Scholz: "Deletion of an intronic HIF-2α binding site suppresses hypoxia-induced WT1 expression." dans: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1862, Issue 1, pp. 71-83, (2019) (PubMed).

Hong, Zhou, Ma, Zhang, Xie, Zhang, Li, Cai, Zhang, Zhang, Gong: "TRIB3 Promotes the Proliferation and Invasion of Renal Cell Carcinoma Cells via Activating MAPK Signaling Pathway." dans: International journal of biological sciences, Vol. 15, Issue 3, pp. 587-597, (2019) (PubMed).

Han, Lee, Kong, Ji, Kim, Choe, Kim: "Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor." dans: Molecular and cellular biology, Vol. 39, Issue 2, (2019) (PubMed).

Liao, Liu, Langbein, Cai, Cho, Na, Niu, Jiang, Zhong, Cai, Jagannathan, Dulaimi, Testa, Uzzo, Wang, Stark, Sun, Peiper, Xu, Yan, Yang: "Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer." dans: eLife, Vol. 7, (2019) (PubMed).

Schwartz, Das, Ramakrishnan, Jain, Jurkovic, Wu, Nemeth, Lakhal-Littleton, Colacino, Shah: "Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload." dans: The Journal of clinical investigation, Vol. 129, Issue 1, pp. 336-348, (2019) (PubMed).

Liu, Luo, Kuang, Xu, Duan, Xia, Wei, Xie, Yin, Chen, Luo, Liu, Wang, Jiang, Gong, Tang, Cheng, Li, Li, Laurence, Wang, Yang: "Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression." dans: The Journal of clinical investigation, Vol. 129, Issue 2, pp. 631-646, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à EPAS1

endothelial PAS domain protein 1 (EPAS1), endothelial PAS domain protein 1 (epas1), endothelial PAS domain protein 1 (Epas1), endothelial PAS domain protein 1 L homeolog (epas1.L), bHLHe73, bhlhe73, ECYT4, ecyt4, EPAS, EPAS-1, EPAS1, HIF-2alpha, hif2, HIF2A, Hif2a, hif2a, hif2alpha, HLF, hlf, HRF, MOP2, mop2, PASD2, pasd2

Protein level used designations for EPAS1

  • endothelial PAS domain protein 1
  • endothelial PAS domain-containing protein 1-like
  • EPAS-1
  • HIF-1-alpha-like factor
  • HIF-1alpha-like factor
  • HIF-2-alpha
  • HIF2-alpha
  • PAS domain-containing protein 2
  • basic-helix-loop-helix-PAS protein MOP2
  • class E basic helix-loop-helix protein 73
  • endothelial PAS domain-containing protein 1
  • hypoxia-inducible factor 2 alpha
  • hypoxia-inducible factor 2-alpha
  • member of PAS protein 2
  • HIF-related factor
  • HIF1 alpha-like factor
  • HIF1alpha-like factor
  • HLF (HIF1alpha-like factor)
  • Hif like protein
  • hypoxia inducible transcription factor 2alpha
  • mHLF
  • HIF-2 alpha
  • HIF2 alpha
  • hypoxia inducible factor 2, alpha subunit
  • hypoxia inducible factor 2a
  • HIF-2alpha
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