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ERCC6L Produits

(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Catégories

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

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Catégories ERCC6L en vedette

ERCC6L Anticorps

High quality antibodies with extensive validation data.

ERCC6L Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ERCC6L recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, WB
Validations
  • (3)
  • (3)
N° du produit ABIN565778
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (3)
N° du produit ABIN527206
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (6)
  • (2)
N° du produit ABIN527207
Quantité 100 μg
Fiche technique Fiche technique

ERCC6L recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6228431
Quantité 96 tests
Fiche technique Fiche technique

ERCC6L recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1353041
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3092403
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3136167
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ERCC6L

Gemble, Buhagiar-Labarchède, Onclercq-Delic, Biard, Lambert, Amor-Guéret: "A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation." dans: Journal of cell science, Vol. 129, Issue 16, pp. 3167-77, (2016) (PubMed).

Nera, Huang, Lai, Xu: "Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions." dans: Nature communications, Vol. 6, pp. 10132, (2015) (PubMed).

Kang, Song, Du, Zhang, Liu, Liang, He, Lamb, Shen, Yin: "PTEN stabilizes TOP2A and regulates the DNA decatenation." dans: Scientific reports, Vol. 5, pp. 17873, (2015) (PubMed).

Luebben, Kawabata, Johnson, OSullivan, Shima: "A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression." dans: Nucleic acids research, Vol. 42, Issue 9, pp. 5605-15, (2014) (PubMed).

Rouzeau, Cordelières, Buhagiar-Labarchède, Hurbain, Onclercq-Delic, Gemble, Magnaghi-Jaulin, Jaulin, Amor-Guéret: "Bloom's syndrome and PICH helicases cooperate with topoisomerase II? in centromere disjunction before anaphase." dans: PLoS ONE, Vol. 7, Issue 4, pp. e33905, (2012) (PubMed).

Muñoz, Laulier, Gunn, Cheng, Robbiani, Nussenzweig, Stark: "RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1." dans: The Journal of biological chemistry, Vol. 287, Issue 48, pp. 40618-28, (2012) (PubMed).

Laulier, Cheng, Stark: "The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation." dans: Nucleic acids research, Vol. 39, Issue 14, pp. 5935-44, (2011) (PubMed).

Kurasawa, Yu-Lee: "PICH and cotargeted Plk1 coordinately maintain prometaphase chromosome arm architecture." dans: Molecular biology of the cell, Vol. 21, Issue 7, pp. 1188-99, (2010) (PubMed).

Leng, Bessuso, Jung, Wang, Qin: "Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase." dans: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 10, pp. 1480-9, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à ERCC6L

ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), excision repair cross-complementing rodent repair deficiency complementation group 6 like (Ercc6l), ERCC excision repair 6 like, spindle assembly checkpoint helicase (Ercc6l), DNA excision repair protein ERCC-6-like (LOC100373376), DNA excision repair protein ERCC-6-like (LOC100494766), DNA excision repair protein ERCC-6-like (LOC100552957), DNA excision repair protein ERCC-6-like (LOC100560751), DNA excision repair protein ERCC-6-like (LOC100563247), excision repair cross-complementation group 6-like (ercc6l), BC004701, D330021P09Rik, fc22h03, PICH, RAD26L, RGD1565734, si:ch211-278b8.3, wu:fc22h03

Protein level used designations for ERCC6L

  • ATP-dependent helicase ERCC6-like
  • DNA excision repair protein ERCC-6-like
  • Plk1-interacting checkpoint helicase
  • SNF2/RAD54 family protein
  • excision repair cross-complementing rodent repair deficiency complementation group 6 - like
  • excision repair protein ERCC6-like
  • tumor antigen BJ-HCC-15
  • excision repair cross-complementing rodent repair deficiency complementation group 6-like
  • excision repair cross-complementing rodent repair deficiency, complementation group 6-like
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