Erythrocyte Ankyrin Produits
(Ankyrin 1, Erythrocytic (ANK1))
Catégories
Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified. [provided by RefSeq, Dec 2008].
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Catégories Erythrocyte Ankyrin en vedette
Erythrocyte Ankyrin Anticorps
High quality antibodies with extensive validation data.
Erythrocyte Ankyrin Kits ELISA
Reliable ELISA kits for a wide range of species.
Erythrocyte Ankyrin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IF
Validations
- (3)
N° du produit
ABIN2485532
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IF
Validations
- (3)
N° du produit
ABIN2485521
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IF
Validations
- (3)
N° du produit
ABIN2485534
Quantité
100 μg
Fiche technique
Fiche technique
Erythrocyte Ankyrin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964879
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1121977
Quantité
96 tests
Fiche technique
Fiche technique
Erythrocyte Ankyrin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345068
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7416055
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Erythrocyte Ankyrin
: "ANK1 Methylation regulates expression of MicroRNA-486-5p and discriminates lung tumors by histology and smoking status." dans: Cancer letters, Vol. 410, pp. 191-200, (2017) (PubMed).: "The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration." dans: Cell death & disease, Vol. 7, pp. e2184, (2016) (PubMed).
: "Upregulated expression of cardiac ankyrin repeat protein in human failing hearts due to arrhythmogenic right ventricular cardiomyopathy." dans: European journal of heart failure, Vol. 11, Issue 6, pp. 559-66, (2009) (PubMed).
: "Functional links between membrane transport and the spectrin cytoskeleton." dans: The Journal of membrane biology, Vol. 211, Issue 3, pp. 151-61, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à Erythrocyte Ankyrin
ankyrin 1 (ANK1), ankyrin 1, erythrocytic a (ank1a), ankyrin 1 (ank1), ankyrin 1 L homeolog (ank1.L), ankyrin 1, erythrocytic (ANK1), ankyrin 1 (Ank1), ankyrin 1, erythroid (Ank1), ank, ANK, Ank-1, ANK1, CHANK1, nb, pale, sph1, SPH1, sph2, SPH2, wu:fa09h06, zgc:101835Protein level used designations for Erythrocyte Ankyrin
- ankyrin 1, erythrocytic
- erythroid ankyrin
- ankyrin-1-like
- ANK-1
- ankyrin-1
- ankyrin-R
- erythrocyte ankyrin
- ankyrin 1, erythroid
- normoblastic anemia
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