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Factor VII Produits

(Coagulation Factor VII (F7))

Catégories

This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].

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Catégories Factor VII en vedette

Factor VII Anticorps

High quality antibodies with extensive validation data.

Factor VII Kits ELISA

Reliable ELISA kits for a wide range of species.

Factor VII Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Factor VII recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7440011
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (3)
N° du produit ABIN515448
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, PLA
Validations
  • (3)
N° du produit ABIN515449
Quantité 100 μg
Fiche technique Fiche technique

Factor VII recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (6)
N° du produit ABIN6574291
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
N° du produit ABIN6574292
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6963490
Quantité 96 tests
Fiche technique Fiche technique

Factor VII recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1353322
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1353324
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7395107
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Factor VII

Santos, Antunes, Souza, Moreira, Lima, Farias-de-Oliveira, Lobo, de Meis, Coura, Savino, Junqueira, de Meis: "Human acute Chagas disease: changes in factor VII, activated protein C and hepatic enzymes from patients of oral outbreaks in Pará State (Brazilian Amazon)." dans: Memórias do Instituto Oswaldo Cruz, Vol. 115, pp. e190364, (2020) (PubMed).

Posthuma, Posma, van Oerle, Leenders, van Gorp, Jaminon, Mackman, Heitmeier, Schurgers, Ten Cate, Spronk: "Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice." dans: Scientific reports, Vol. 9, Issue 1, pp. 3909, (2019) (PubMed).

Gaul, Weber, van Tits, Sluka, Pasterk, Reiner, Calatayud, Lohmann, Klingenberg, Pahla, Vdovenko, Tanner, Camici, Eriksson, Auwerx, Mach, Windecker, Rodondi, Lüscher, Winnik, Matter: "Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity." dans: Cardiovascular research, Vol. 114, Issue 8, pp. 1178-1188, (2018) (PubMed).

Teligui, Dalmayrac, Corbeau, Bouquet, Godon, Denommé, Binuani, Verron, Boer, Baufreton: "Ex vivo simulation of cardiopulmonary bypass with human blood for hemocompatibility testing." dans: Perfusion, Vol. 31, Issue 5, pp. 376-83, (2016) (PubMed).

Mahlangu, Paz, Hardtke, Aswad, Schroeder: "TRUST trial: BAY 86-6150 use in haemophilia with inhibitors and assessment for immunogenicity." dans: Haemophilia : the official journal of the World Federation of Hemophilia, Vol. 22, Issue 6, pp. 873-879, (2016) (PubMed).

Schut, Kirschbaum, Adelmeijer, de Groot, Lisman: "In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug." dans: British journal of haematology, (2016) (PubMed).

Wang, Braun, Zhang, Norström, Thorlacius: "Monocytes regulate systemic coagulation and inflammation in abdominal sepsis." dans: American journal of physiology. Heart and circulatory physiology, Vol. 308, Issue 5, pp. H540-7, (2015) (PubMed).

Naderi: "Coagulation factor VII is regulated by androgen receptor in breast cancer." dans: Experimental cell research, Vol. 331, Issue 1, pp. 239-50, (2015) (PubMed).

Li, Wang, Long, Su, Bukhory, Dai, Jin, Huang, Jia, Li, Fan, Liu, Wang: "Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity." dans: PLoS ONE, Vol. 9, Issue 4, pp. e94551, (2014) (PubMed).

Di Bitondo, Hall, Peake, Iacoviello, Winship: "Oestrogenic repression of human coagulation factor VII expression mediated through an oestrogen response element sequence motif in the promoter region." dans: Human molecular genetics, Vol. 11, Issue 7, pp. 723-31, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à Factor VII

coagulation factor VII (F7), coagulation factor VII (f7), serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 (Serpinc1), coagulation factor VII (CpipJ_CPIJ009142), coagulation factor VII (CpipJ_CPIJ010295), coagulation factor VII (CpipJ_CPIJ020127), coagulation factor VII (fa7), coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog (f7.S), AI114908, AI132620, At-3, At3, ATIII, Cf7, F7, f7, FVII, LOC100223776, mfVII, SPCA, wu:fb59f04, zgc:109870

Protein level used designations for Factor VII

  • coagulation factor VII
  • serum prothrombin conversion accelerator
  • clotting factor
  • FVII coagulation protein
  • eptacog alfa
  • proconvertin
  • anti-thrombin 3
  • antithrombin
  • antithrombin-III
  • serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
  • serpin C1
  • serpin peptidase inhibitor, clade C, member 1
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