Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

FADD Produits

(Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Catégories

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories FADD en vedette

FADD Anticorps

High quality antibodies with extensive validation data.

FADD Kits ELISA

Reliable ELISA kits for a wide range of species.

FADD Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FADD recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7439960
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (1)
  • (4)
N° du produit ABIN6140432
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IP, IF
Validations
  • (4)
N° du produit ABIN7267137
Quantité 100 μL
Fiche technique Fiche technique

FADD recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966647
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955701
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380169
Quantité 2 x 96 tests
Fiche technique Fiche technique

FADD recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1353355
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1353353
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3122886
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits FADD

Lindstrom, Sigurdardottir, Zapadka, Tang, Liu, Taylor, Smith, Lee, DeAngelis, Kern, Taylor: "Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration." dans: Journal of diabetes and its complications, Vol. 33, Issue 9, pp. 668-674, (2019) (PubMed).

Li, Mo, Lei, Li, Fu, Huang, Luo, Zhang: "Edaravone attenuates neuronal apoptosis in hypoxic-ischemic brain damage rat model via suppression of TRAIL signaling pathway." dans: The international journal of biochemistry & cell biology, Vol. 99, pp. 169-177, (2018) (PubMed).

Cai, Lv, Kaldybayeva, Zhamilya, Wu, Wu: "15, 16-Dihydrotanshinone I Inhibits Hemangiomas through Inducing Pro-apoptotic and Anti-angiogenic Mechanisms in Vitro and in Vivo." dans: Frontiers in pharmacology, Vol. 9, pp. 25, (2018) (PubMed).

Tian, Yao, Yang, Ren, Jiao, Zhang, Li, Zhang, Xia, Qin: "D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway." dans: Scientific reports, Vol. 7, Issue 1, pp. 7333, (2017) (PubMed).

Soni, Adebiyi: "Early septic insult in neonatal pigs increases serum and urinary soluble Fas ligand and decreases kidney function without inducing significant renal apoptosis." dans: Renal failure, pp. 1-12, (2016) (PubMed).

Papoff, Trivieri, Crielesi, Ruberti, Marsilio, Ruberti: "FADD-calmodulin interaction: a novel player in cell cycle regulation." dans: Biochimica et biophysica acta, Vol. 1803, Issue 8, pp. 898-911, (2010) (PubMed).

Li, Jayarama, Ganesh, Mordi, Carr, Kanteti, Hay, Prabhakar: "Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4." dans: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22713-22, (2010) (PubMed).

Ko, Yang, Chung, Wen, Hsu, Miaw, Hsia: "Lack of Fas-pathway gene mutations in primary resected esophageal squamous cell carcinoma." dans: Chang Gung medical journal, Vol. 33, Issue 2, pp. 145-51, (2010) (PubMed).

Hindryckx, De Vos, Jacques, Ferdinande, Peeters, Olievier, Bogaert, Brinkman, Vandenabeele, Elewaut, Laukens: "Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 10, pp. 6306-16, (2010) (PubMed).

Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: "Dengue hemorrhagic fever is associated with polymorphisms in JAK1." dans: European journal of human genetics : EJHG, Vol. 18, Issue 11, pp. 1221-7, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à FADD

Fas associated via death domain (FADD), Fas (TNFRSF6)-associated via death domain (Fadd), Fas associated via death domain (Fadd), Fas associated via death domain S homeolog (fadd.S), Fas (tnfrsf6)-associated via death domain (fadd), adaptor, fadd, MORT1, Mort1, mort1, Mort1/FADD, TNFRSF6, xfadd

Protein level used designations for FADD

  • Fas-associating death domain-containing protein
  • Fas-associating protein with death domain
  • growth-inhibiting gene 3 protein
  • mediator of receptor induced toxicity
  • mediator of receptor-induced toxicity
  • protein FADD
  • FAS-associated death domain protein
  • FAS-associating death domain-containing protein
  • Fas (TNF receptor superfamily, member 6)
  • Fas-associated via death domain
  • Fas (TNFRSF6)-associated via death domain
  • Fas associated via death domain S homeolog
Vous êtes ici:
Support technique