FAM84A Protéines
(Family with Sequence Similarity 84, Member A (FAM84A))
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus.
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FAM84A
Origine: Humain
Hôte: Wheat germ
Recombinant
ELISA, AA, AP, WB
1 image
FAM84A
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
1 image
FAM84A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
FAM84A
Origine: Boeuf (Vache)
Hôte: Levure
Recombinant
> 90 %
ELISA
Dernières publications pour nos FAM84A Protéines
: "Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 28, pp. 7864-9, (2016) (PubMed).Pseudonymes pour FAM84A Protéines
family with sequence similarity 84, member A (Fam84a) Protéinesfamily with sequence similarity 84 member A (FAM84A) Protéines
family with sequence similarity 84, member A (fam84a) Protéines
family with sequence similarity 84 member A (Fam84a) Protéines
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