FAM84A Protein (AA 1-292) (His tag)

N° du produit ABIN5853108

Détail du produit

Antigène: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Type de proteíne: Recombinant

Attributs du protein: AA 1-292

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FAM84A protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMGNQLDR ITHLNYSELP TGDPSGIEKD ELRVGVAYFF SDDEEDLDER GQPDKFGVKA PPGCTPCPES PSRHHHHLLH QLVLNETQFS AFRGQECIFS KVSGGPQGAD LSVYAVTALP ALCEPGDLLE LLWLQPAPEP PAPAPHWAVY VGGGQIIHLH QGEIRQDSLY EAGAANVGRV VNSWYRYRPL VAELVVQNAC GHLGLKSEEI CWTNSESFAA WCRFGKREFK AGGEVPAGTQ PPQQQYYLKV HLGENKVHTA RFHSLEDLIR EKRRIDASGR LRVLQELADL VDDKE

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Autre désignation: FAM84A (FAM84A Produits)

Synonymes: 2310003N02Rik Protein, 4731402F03Rik Protein, AW125753 Protein, Nse1 Protein, NSE1 Protein, PP11517 Protein, RGD1305779 Protein, zgc:63724 Protein, family with sequence similarity 84, member A Protein, family with sequence similarity 84 member A Protein, Fam84a Protein, FAM84A Protein, fam84a Protein

Sujet: FAM84A belongs to the FAM84 family of proteins and is predominantly expressed in testis. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. FAM84A is up-regulated in colorectal cancer lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells. Recombinant human FAM84A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 34.9kDa (315aa), confirmed by MALDI-TOF

NCBI Accession: NP_660158

UniProt: Q96KN4