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FCAR Produits

(Fc Fragment of IgA, Receptor For (FCAR))

Catégories

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Catégories FCAR en vedette

FCAR Anticorps

High quality antibodies with extensive validation data.

FCAR Kits ELISA

Reliable ELISA kits for a wide range of species.

FCAR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FCAR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC, Neut
Validations
  • (4)
N° du produit ABIN5684138
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7443131
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Non-Human Primate
Application FACS
Validations
  • (2)
N° du produit ABIN4888509
Quantité 0.1 mg
Fiche technique Fiche technique

FCAR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955737
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4882811
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN776794
Quantité 96 tests
Fiche technique Fiche technique

FCAR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274249
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1353885
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7321241
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits FCAR

Björklund, Carlsten, Sohlberg, Liu, Clancy, Karimi, Cooley, Miller, Klimkowska, Schaffer, Watz, Wikström, Blomberg, Wahlin, Palma, Hansson, Ljungman, Hellström-Lindberg, Ljunggren, Malmberg: "Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 8, pp. 1834-1844, (2018) (PubMed).

Moresco, Speeckaert, Zmonarski, Krajewska, Komuda-Leszek, Perkowska-Ptasinska, Gesualdo, Rocchetti, Delanghe, Vanholder, Van Biesen, Delanghe: "Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis." dans: BBA clinical, Vol. 5, pp. 79-84, (2016) (PubMed).

Matt, Lindqvist, Kleinau: "Elevated Membrane and Soluble CD64: A Novel Marker Reflecting Altered Fc?R Function and Disease in Early Rheumatoid Arthritis That Can Be Regulated by Anti-Rheumatic Treatment." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0137474, (2015) (PubMed).

Lu, Marjon, Marnell, Wang, Mold, Du Clos, Sun: "Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 12, pp. 4974-9, (2011) (PubMed).

Duc, Johansen, Corthésy: "Antigen binding to secretory immunoglobulin A results in decreased sensitivity to intestinal proteases and increased binding to cellular Fc receptors." dans: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 953-60, (2010) (PubMed).

Yin, Peng, Xing, Zhang: "Intracellular pools of FcalphaR (CD89) in human neutrophils are localized in tertiary granules and secretory vesicles, and two FcalphaR isoforms are found in tertiary granules." dans: Journal of leukocyte biology, Vol. 82, Issue 3, pp. 551-8, (2007) (PubMed).

Zhang, Bi, Oldroyd, Lachmann: "Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a." dans: Clinical and experimental immunology, Vol. 121, Issue 1, pp. 106-11, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à FCAR

Fc fragment of IgA receptor (FCAR), Fc fragment of IgA, receptor for (FCAR), CD89

Protein level used designations for FCAR

  • IgA Fc receptor
  • immunoglobulin A Fc receptor
  • immunoglobulin alpha Fc receptor
  • Fc fragment of IgA, receptor for, isoform 7
  • Fc alpha receptor
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