FCAR Protein (AA 22-227) (His tag)
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- Antigène Voir toutes FCAR Protéines
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 22-227
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Origine
- Humain
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Source
- Baculovirus infected Insect Cells
- Purification/Conjugué
- Cette FCAR protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- ADPQEGDFPM PFISAKSSPV IPLDGSVKIQ CQAIREAYLT QLMIIKNSTY REIGRRLKFW NETDPEFVID HMDANKAGRY QCQYRIGHYR FRYSDTLELV VTGLYGKPFL SADRGLVLMP GENISLTCSS AHIPFDRFSL AKEGELSLPQ HQSGEHPANF SLGPVDLNVS GIYRCYGWYN RSPYLWSFPS NALELVVTDS IHQDYTTQNH HHHHH
- Pureté
- > 85 % by SDS - PAGE
- niveau d'endotoxine
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product FCAR Protéine
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Fc Fragment of IgA, Receptor For (FCAR) protein (His tag)
FCAR Origine: Humain Hôte: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgA, Receptor For (FCAR) (AA 24-133) protein (GST tag)FCAR Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Fc Fragment of IgA, Receptor For (FCAR) protein (His tag)FCAR Origine: Rat Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Fc Fragment of IgA, Receptor For (FCAR) (AA 22-227) protein (His tag)Crystallography grade FCAR Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fc Fragment of IgA, Receptor For (FCAR) (AA 22-287) protein (rho-1D4 tag)Crystallography grade FCAR Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- Autre désignation
- FCAR (FCAR Produits)
- Synonymes
- CD89 Protein, Fc fragment of IgA receptor Protein, Fc fragment of IgA, receptor for Protein, FCAR Protein
- Sujet
- FCAR, also known as immunoglobulin alpha Fc receptor isoform, is a member of the multichain immune recognition receptor family which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. It plays a role in both pro- and anti-inflammatory responses depending on the state of IgA bound. It is also an important Fc receptor for neutrophil killing of tumor cells. When FCAR expressing neutrophils come into contact with IgA-opsonized tumor cells, the neutrophils not only perform antibody-dependent cell-mediated cytotoxicity, but also release the cytokines TNF-alpha and IL-1beta which cause increased neutrophil migration to the site. Recombinant human FCAR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Poids moléculaire
- 24.5kDa (215aa) 28-40kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_001991
- UniProt
- P24071
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