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FCGR3A Protéines

(Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

31 Résultats

FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SEC-HPLC, SPR
N° du produit ABIN7536872
 
FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SEC-HPLC, SPR
N° du produit ABIN7536871
 
FCGR3A Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
N° du produit ABIN1353901
 
FCGR3A Origine: Cynomolgus Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7321023
 
FCGR3A Origine: Humain Hôte: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
N° du produit ABIN7607284
 
FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN6961127
 
FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. Active
N° du produit ABIN7195697
 
FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
N° du produit ABIN7195704
 
FCGR3A Origine: Rat Hôte: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
N° du produit ABIN7195703
 
FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
N° du produit ABIN7317018
 
FCGR3A Origine: Souris Hôte: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
N° du produit ABIN2870739
 
FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN2870544
 
FCGR3A Origine: Humain Hôte: Mammalian Cells Recombinant Greater than 95 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7663733
 
FCGR3A Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN6573507
 
FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7504321
 
FCGR3A Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7597356
 
FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
N° du produit ABIN7534705
 
FCGR3A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
N° du produit ABIN7393661
 
FCGR3A Origine: Humain Recombinant BCA
N° du produit ABIN1685422
 
FCGR3A Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
N° du produit ABIN7535300
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Activity Assay (AcA)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Size-exclusion chromatography-High Pressure Liquid Chromatography (SEC-HPLC)
    • Surface Plasmon Resonance (SPR)
    • Antibody Array (AA)
    • Biochemical Assay (BCA)
    • Mass Spectrometry (MS)
  • Réactivité
    • Human
    • Mouse
    • Rat
    • Cynomolgus
  • Cité dans publications
  • Images disponible
  • Sans conservateur uniquement
  • Carrier free only
  • Hote
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Human Cells
    • Mammalian Cells
    • Wheat germ
    • Baculovirus infected Insect Cells
  • Epitope
    • AA 17-208
    • AA 17-206
    • AA 18-208
    • AA 107-189
    • AA 17-254
    • AA 26-108
    • AA 32-215
    • AA 5-240
    • AA 5-241
    • F176V
    • Phe176Val
    • V176F
    • Val176Phe-Mutant
  • Conjugué
    • His tag
    • Inconjugué
    • His tag,GST tag
    • Biotin,His-Avi Tag
    • Fc Tag
    • Fc Tag,His tag
    • GST tag
    • HSA,His tag
    • His tag,AVI tag
    • His tag,AVI tag,Biotin
    • His tag,SUMO Tag
    • His-Avi Tag
    • His-Avi Tag,Biotin
    • mFc Tag
  • Type Proteine
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Activité biologique
    • Biologically Active
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • Abbexa
    • Cohesion Biosciences

Dernières publications pour nos FCGR3A Protéines

de Taeye, Bentlage, Mebius, Meesters, Lissenberg-Thunnissen, Falck, Sénard, Salehi, Wuhrer, Schuurman, Labrijn, Rispens, Vidarsson: "FcγR Binding and ADCC Activity of Human IgG Allotypes." dans: Frontiers in immunology, Vol. 11, pp. 740, (2020) (PubMed).

Aoyama, Hashii, Tsukimura, Osumi, Harazono, Tada, Kiyoshi, Matsuda, Ishii-Watabe: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." dans: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." dans: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Zhao, Li, Wu, Li, Liu, Wang, Liu, Li, Wang: "Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies." dans: Cancer biology & therapy, pp. 1-9, (2019) (PubMed).

Huang, Li, Liu, Ye, Fan, Yuan, Wu, Chen, Jin, Shen, Feng, Zhang: "Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody." dans: mAbs, Vol. 10, Issue 6, pp. 864-875, (2019) (PubMed).

Dakshinamurthy, Mukunda, Prasad Kodaganti, Shenoy, Natarajan, Maliwalave, Halan, Murugesan, Maity: "Charge variant analysis of proposed biosimilar to Trastuzumab." dans: Biologicals : journal of the International Association of Biological Standardization, Vol. 46, pp. 46-56, (2017) (PubMed).

Hayes, Frostell, Cosgrave, Struwe, Potter, Davey, Karlsson, Anneren, Rudd: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." dans: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).

Sakamoto, Ito, Hatanaka, Soni, Mori, Sugimura: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." dans: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).

Pseudonymes pour FCGR3A Protéines

Fc fragment of IgG receptor IIIa (FCGR3A) Protéines
Fc fragment of IgG receptor IIIa (Fcgr3a) Protéines
CD16 Protéines
CD16A Protéines
FCG3 Protéines
FCGR3 Protéines
Fcgr4 Protéines
FCGRIII Protéines
FCR-10 Protéines
FCRIII Protéines
FCRIIIA Protéines
IGFR3 Protéines
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