FCGR3A Protéines
(Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Filtrer les résultats:
36 Résultats
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % by SEC-HPLC
SDS, SEC-HPLC, SPR
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % by SEC-HPLC
SDS, SEC-HPLC, SPR
FCGR3A
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
FCGR3A
Origine: Cynomolgus
Hôte: Human Cells
Recombinant
>95 % as determined by reducing SDS-PAGE.
1 image
FCGR3A
Origine: Humain
Hôte: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
SDS, WB, Imm, ELISA, AcA
Active
1 image
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 97 % as determined by reducing SDS-PAGE.
Active
1 image
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Active
1 image
FCGR3A
Origine: Rat
Hôte: HEK-293 Cells
Recombinant
> 97 % as determined by SDS-PAGE
Active
1 image
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
1 image
FCGR3A
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
>95 % as determined by reduced SDS-PAGE.
Active
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
Active
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
FCGR3A
Origine: Humain
Hôte: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
FCGR3A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
FCGR3A
Origine: Humain
Hôte: Mammalian Cells
Recombinant
Greater than 95 % as determined by SDS-PAGE.
WB, ELISA
FCGR3A
Origine: Cynomolgus
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
FCGR3A
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
Dernières publications pour nos FCGR3A Protéines
: "FcγR Binding and ADCC Activity of Human IgG Allotypes." dans: Frontiers in immunology, Vol. 11, pp. 740, (2020) (PubMed).: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." dans: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).
: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." dans: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).
: "Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies." dans: Cancer biology & therapy, pp. 1-9, (2019) (PubMed).
: "Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody." dans: mAbs, Vol. 10, Issue 6, pp. 864-875, (2019) (PubMed).
: "Charge variant analysis of proposed biosimilar to Trastuzumab." dans: Biologicals : journal of the International Association of Biological Standardization, Vol. 46, pp. 46-56, (2017) (PubMed).
: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." dans: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).
: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." dans: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).
Pseudonymes pour FCGR3A Protéines
Fc fragment of IgG receptor IIIa (FCGR3A) ProtéinesFc fragment of IgG receptor IIIa (Fcgr3a) Protéines
CD16 Protéines
CD16A Protéines
FCG3 Protéines
FCGR3 Protéines
Fcgr4 Protéines
FCGRIII Protéines
FCR-10 Protéines
FCRIII Protéines
FCRIIIA Protéines
IGFR3 Protéines
Avez-vous cherché autre chose?
- FCGR2B Protéines
- FCGR2A Protéines
- FCGR1A Protéines
- FCGR1 Protéines
- FCGBP Protéines
- FCF1 Protéines
- FCER2 Protéines
- FCAR Protéines
- FCAMR Protéines
- Fc Receptor, IgG, Low Affinity IV Protéines
- Fc gamma RII Protéines
- Fc epsilon RI/FCER1A Protéines
- FBXW9 Protéines
- FBXW8 Protéines
- FBXW7 Protéines
- FBXW5 Protéines
- FBXW4 Protéines
- FBXW2 Protéines
- FBXW11 Protéines
- FBXO9 Protéines
- FCGR3B Protéines
- FCN1 Protéines
- FCN3 Protéines
- FCRL1 Protéines
- FCRL2 Protéines
- FCRL4 Protéines
- FCRL5 Protéines
- FCRL6 Protéines
- FCRLA Protéines
- FDCSP Protéines
- FDFT1 Protéines
- FDPS Protéines
- FDX1L Protéines
- FDXACB1 Protéines
- FE65 Protéines
- FECH Protéines
- FEM1A Protéines
- FEM1B Protéines
- FEM1C Protéines
- FEN1 Protéines
Vous êtes ici:
