FE65 Protéines
(Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012].
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APBB1
Origine: Humain
Hôte: Wheat germ
Recombinant
ELISA, WB, AA, AP
1 image
custom-made
APBB1
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
APBB1
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
APBB1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
1 image
APBB1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
APBB1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Pseudonymes pour FE65 Protéines
amyloid beta precursor protein binding family B member 1 (APBB1) Protéinesamyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog (apbb1.L) Protéines
amyloid beta (A4) precursor protein-binding, family B, member 1 (Apbb1) Protéines
amyloid beta precursor protein binding family B member 1 (Apbb1) Protéines
apbb1 Protéines
FE65 Protéines
Fe65 Protéines
MGC80654 Protéines
MGC:9072 Protéines
RIR Protéines
Rir Protéines
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