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neonatal Fc Receptor Protéines

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

Filtres sélectionnés

  • Target: FcRn
  • Protein
Catalog no. Produit Reactivité Hôte / Clonalité Application Prix et délai de livraison
ABIN7866698
FcRn Protein (AA 24-297) (His tag) FcRn · Protein Humain HEK-293 Cells
789,23 € Voir le prix
  • 50 μg
Envoi sous 6 à 9 jours ouvrables Destination: France
ABIN7950699
FcRn Protein (His tag) FcRn · Protein Souris Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Application indiquée)
  • WB (Western Blotting: Application indiquée)
  • Imm (Immunogen: Application indiquée)
  • ELISA (ELISA: Application indiquée)
503,00 € Voir le prix
  • 100 μg
  • 1 mg
  • 50 μg
Envoi sous 12 à 17 jours ouvrables Destination: France
ABIN7943515
FcRn Protein (His tag) FcRn · Protein Humain Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Application indiquée)
  • WB (Western Blotting: Application indiquée)
  • Imm (Immunogen: Application indiquée)
  • ELISA (ELISA: Application indiquée)
503,00 € Voir le prix
  • 100 μg
  • 1 mg
  • 50 μg
Envoi sous 12 à 17 jours ouvrables Destination: France
ABIN2720991
FcRn Protein (Transcript Variant 2) FcRn · Protein Humain HEK-293 Cells
  • AbP (Antibody Production: Application indiquée)
  • STD (Standard: Application indiquée)
394,23 € Voir le prix
  • 10 μg
Envoi sous 8 à 14 jours ouvrables Destination: France
Protein
Origine
Humain
Hôte
HEK-293 Cells
Type Proteine
Recombinant
Pureté
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7866698
789,23 €
Plus frais de livraison 40,00 € et TVA
50 μg
Destination: France
Envoi sous 6 à 9 jours ouvrables
Protein
  • SDS (SDS-PAGE: Application indiquée)
  • WB (Western Blotting: Application indiquée)
  • Imm (Immunogen: Application indiquée)
  • ELISA (ELISA: Application indiquée)
Origine
Souris
Hôte
Escherichia coli (E. coli)
Type Proteine
Recombinant
N° du produit ABIN7950699
503,00 €
Plus frais de livraison 40,00 € et TVA
100 μg (Autres quantités disponibles)
Destination: France
Envoi sous 12 à 17 jours ouvrables
Protein
  • SDS (SDS-PAGE: Application indiquée)
  • WB (Western Blotting: Application indiquée)
  • Imm (Immunogen: Application indiquée)
  • ELISA (ELISA: Application indiquée)
Origine
Humain
Hôte
Escherichia coli (E. coli)
Type Proteine
Recombinant
N° du produit ABIN7943515
503,00 €
Plus frais de livraison 40,00 € et TVA
100 μg (Autres quantités disponibles)
Destination: France
Envoi sous 12 à 17 jours ouvrables
Protein
  • AbP (Antibody Production: Application indiquée)
  • STD (Standard: Application indiquée)
Origine
Humain
Hôte
HEK-293 Cells
Type Proteine
Recombinant
Pureté
> 95 % as determined by SDS-PAGE and Coomassie blue staining
N° du produit ABIN2720991
394,23 €
Frais d'envoi 40,00 €, glace carbonique 20,00 € et TVA exclus
10 μg
Destination: France
Envoi sous 8 à 14 jours ouvrables

Dernières publications pour nos neonatal Fc Receptor Protéines

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." dans: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." dans: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." dans: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." dans: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." dans: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." dans: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." dans: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." dans: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." dans: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Pseudonymes pour neonatal Fc Receptor Protéines

Fc fragment of IgG receptor and transporter (FCGRT) Protéines
Fc fragment of IgG receptor and transporter (Fcgrt) Protéines
Fc receptor, IgG, alpha chain transporter (Fcgrt) Protéines
alpha-chain Protéines
FCRN Protéines
FcRn Protéines
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