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FHL1 Produits

(Four and A Half LIM Domains 1 (FHL1))

Catégories

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009].

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Catégories FHL1 en vedette

FHL1 Anticorps

High quality antibodies with extensive validation data.

FHL1 Kits ELISA

Reliable ELISA kits for a wide range of species.

FHL1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FHL1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (6)
N° du produit ABIN560899
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IF, IC
Validations
  • (2)
  • (1)
N° du produit ABIN7306298
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Application WB, IHC
Validations
  • (12)
  • (4)
N° du produit ABIN2775759
Quantité 100 μL
Fiche technique Fiche technique

FHL1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955987
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4882885
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1133659
Quantité 96 tests
Fiche technique Fiche technique

FHL1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354072
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354074
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3080101
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits FHL1

Meertens, Hafirassou, Couderc, Bonnet-Madin, Kril, Kümmerer, Labeau, Brugier, Simon-Loriere, Burlaud-Gaillard, Doyen, Pezzi, Goupil, Rafasse, Vidalain, Bertrand-Legout, Gueneau, Juntas-Morales et al.: "FHL1 is a major host factor for chikungunya virus infection. ..." dans: Nature, Vol. 574, Issue 7777, pp. 259-263, (2019) (PubMed).

Le Thanh, Meinke, Korfali, Srsen, Robson, Wehnert, Schoser, Sewry, Schirmer: "Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology." dans: Neuromuscular disorders : NMD, Vol. 27, Issue 4, pp. 338-351, (2017) (PubMed).

Xue, Schoser, Rao, Quadrelli, Vaglio, Rupp, Beichler, Nelson, Schapacher-Tilp, Windpassinger, Wilcox: "Exome Sequencing Identified a Splice Site Mutation in FHL1 that Causes Uruguay Syndrome, an X-Linked Disorder With Skeletal Muscle Hypertrophy and Premature Cardiac Death." dans: Circulation. Cardiovascular genetics, Vol. 9, Issue 2, pp. 130-5, (2016) (PubMed).

Emmanuele, Kubota, Garcia-Diaz, Garone, Akman, Sánchez-Gutiérrez, Escudero, Kariya, Homma, Tanji, Quinzii, Hirano: "Fhl1 W122S causes loss of protein function and late-onset mild myopathy." dans: Human molecular genetics, Vol. 24, Issue 3, pp. 714-26, (2015) (PubMed).

Albrecht, Wick, Hallgren, Tjärnlund, Nagaraju, Andrade, Thompson, Coley, Phadke, Diaz-Gallo, Bottai, Nennesmo, Chemin, Herrath, Johansson, Wikberg, Ytterberg, Zubarev, Danielsson, Krystufkova et al.: "Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies. ..." dans: The Journal of clinical investigation, Vol. 125, Issue 12, pp. 4612-24, (2015) (PubMed).

Ma, Mao, Shen, Zheng, Li, Liu, Ni: "Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits." dans: Biochemical and biophysical research communications, Vol. 450, Issue 1, pp. 353-9, (2014) (PubMed).

Zhang, Chen, Sharma, Moon, Sheftel, Dawood, Nghiem, Wu, Li, Gramolini, Sorensen, Penninger, Brumell, Liu: "HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress." dans: Nature communications, Vol. 5, pp. 3430, (2014) (PubMed).

Fujii, Hayashi, Kawamura, Higuchi, Tsugawa, Ohyagi, Hayashi, Nishino, Kira: "A case of adult-onset reducing body myopathy presenting a novel clinical feature, asymmetrical involvement of the sternocleidomastoid and trapezius muscles." dans: Journal of the neurological sciences, Vol. 343, Issue 1-2, pp. 206-10, (2014) (PubMed).

Koike, Kasamatsu, Iyoda, Saito, Kouzu, Koike, Sakamoto, Ogawara, Tanzawa, Uzawa: "High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer." dans: International journal of oncology, Vol. 42, Issue 1, pp. 141-50, (2012) (PubMed).

Sharma, Shathasivam, Ignatchenko, Kislinger, Gramolini: "Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis." dans: Molecular bioSystems, Vol. 7, Issue 4, pp. 1185-96, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à FHL1

four and a half LIM domains 1 (fhl1), four and a half LIM domains 1 (FHL1), four and a half LIM domains 1a (fhl1a), Four and a half LIM domains protein 1 (fhl1), four and a half LIM domains 1 S homeolog (fhl1.S), four and a half LIM domains 1 (Fhl1), DKFZp468O1927, fhl, FHL-1, fhl1, FHL1, Fhl1, FHL1A, FHL1B, fhla, FLH1A, KYOT, KyoT, MGC89165, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA, zgc:92025

Protein level used designations for FHL1

  • four and a half LIM domains 1
  • four and a half LIM domains protein 1-like
  • four and a half LIM domains a
  • four and a half LIM domains protein 1
  • Four and a half LIM domains protein 1
  • four and a half lim domains protein 1
  • LIM protein SLIMMER
  • four-and-a-half Lin11, Isl-1 and Mec-3 domains 1
  • skeletal muscle LIM-protein 1
  • FHL-1
  • RAM14-1
  • RBP-associated molecule 14-1
  • SLIM
  • SLIM-1
  • four and a half LIM domains 1 protein
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