FHIT Produits
(Fragile Histidine Triad (FHIT))
Catégories
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009].
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Catégories FHIT en vedette
FHIT Anticorps
High quality antibodies with extensive validation data.
FHIT Kits ELISA
Reliable ELISA kits for a wide range of species.
FHIT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FHIT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (4)
N° du produit
ABIN3021692
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (4)
N° du produit
ABIN3042392
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, WB, IHC, IF, ICC
Validations
- (3)
N° du produit
ABIN6261741
Quantité
100 μL
Fiche technique
Fiche technique
FHIT recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975306
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1381137
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6951726
Quantité
96 tests
Fiche technique
Fiche technique
FHIT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123000
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354070
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3132324
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits FHIT
: "FHIT, a Novel Modifier Gene in Pulmonary Arterial Hypertension." dans: American journal of respiratory and critical care medicine, Vol. 199, Issue 1, pp. 83-98, (2019) (PubMed).: "FHIT promoter methylation status, low protein and high mRNA levels in patients with non-small cell lung cancer." dans: International journal of oncology, Vol. 49, Issue 3, pp. 1175-84, (2016) (PubMed).
: "High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesis." dans: Neoplasia (New York, N.Y.), Vol. 14, Issue 9, pp. 788-98, (2012) (PubMed).
: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." dans: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, (2010) (PubMed).
: "Neuroprotective properties of picroside II in a rat model of focal cerebral ischemia." dans: International journal of molecular sciences, Vol. 11, Issue 11, pp. 4580-90, (2010) (PubMed).
: "The protein expression of TRP-1 and galectin-1 in cutaneous malignant melanomas." dans: Cancer genomics & proteomics, Vol. 5, Issue 6, pp. 293-300, (2009) (PubMed).
: "Muir-Torre-like syndrome in Fhit-deficient mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 9, pp. 4742-7, (2000) (PubMed).
: "The Fhit tumor suppressor protein regulates the intracellular concentration of diadenosine triphosphate but not diadenosine tetraphosphate." dans: Cancer research, Vol. 60, Issue 9, pp. 2342-4, (2000) (PubMed).
: "The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers." dans: Cell, Vol. 84, Issue 4, pp. 587-97, (1996) (PubMed).
: "Coxsackievirus B3: primary structure of the 5' non-coding and capsid protein-coding regions of the genome." dans: Virus research, Vol. 3, Issue 3, pp. 263-70, (1986) (PubMed).
Synonymes et noms alternatifs relatifs à FHIT
fragile histidine triad (FHIT), fragile histidine triad (Fhit), fragile histidine triad gene (fhit), fragile histidine triad gene (Fhit), fragile histidine triad (fhit), fragile histidine triad protein (PY07476), fragile histidine triad L homeolog (fhit.L), AP3Aase, AW045638, FHIT, FRA3B, Fra14A2, LOC100223655, zgc:73176Protein level used designations for FHIT
- AP3A hydrolase
- bis(5'-adenosyl)-triphosphatase
- diadenosine 5',5'''-P1,P3-triphosphate hydrolase
- dinucleosidetriphosphatase
- tumor suppressor protein
- AP3Aase
- fragile histidine triad protein
- fragile histidine triad gene
- diadenosine triphosphate hydrolase
- fragile histidine triad
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