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Fibulin 5 Produits

(Fibulin 5 (FBLN5))
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008].

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Catégories Fibulin 5 en vedette

Fibulin 5 Anticorps

High quality antibodies with extensive validation data.

Fibulin 5 Kits ELISA

Reliable ELISA kits for a wide range of species.

Fibulin 5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Fibulin 5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN728473
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7438958
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN6140497
Quantité 100 μL
Fiche technique Fiche technique

Fibulin 5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955903
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966819
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966820
Quantité 96 tests
Fiche technique Fiche technique

Fibulin 5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN2752787
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3080115
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3120153
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Fibulin 5

Sun, Tomita, Salinger, Tilvawala, Li, Hakami, Liu, Tsoyi, Rosas, Reinhardt, Thompson, Ho: "PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis." dans: Matrix biology : journal of the International Society for Matrix Biology, Vol. 102, pp. 70-84, (2022) (PubMed).

Dekker, van Geemen, van den Bogaerdt, Driessen-Mol, Aikawa, Smits: "Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves." dans: Frontiers in cardiovascular medicine, Vol. 5, pp. 105, (2018) (PubMed).

Hu, Dong, Zhao, Xu, Qin: "Fibulin-5: a novel biomarker for evaluating severity and predicting prognosis in patients with acute intracerebral haemorrhage." dans: European journal of neurology, Vol. 23, Issue 7, pp. 1195-201, (2016) (PubMed).

Guo, Cheng, Chen, Xing, Xu, Feng, Qin: "Overexpression of Fibulin-5 Attenuates Ischemia/Reperfusion Injury After Middle Cerebral Artery Occlusion in Rats." dans: Molecular neurobiology, (2015) (PubMed).

Sideek, Menz, Parsi, Gibson: "LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis." dans: Matrix biology : journal of the International Society for Matrix Biology, Vol. 34, pp. 114-23, (2014) (PubMed).

Albig, Neil, Schiemann: "Fibulins 3 and 5 antagonize tumor angiogenesis in vivo." dans: Cancer research, Vol. 66, Issue 5, pp. 2621-9, (2006) (PubMed).

Wen, Hochholdinger, Sauer, Bruce, Schnable: "The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis." dans: Plant physiology, Vol. 138, Issue 3, pp. 1637-43, (2005) (PubMed).

Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." dans: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, (2005) (PubMed).

Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." dans: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à Fibulin 5

fibulin 5 (fbln5), fibulin 5 (FBLN5), fibulin 5 (Fbln5), A55, ADCL2, ARCL1A, ARMD3, DANCE, DKFZp469K0327, EVEC, FBLN5, FIBL-5, Fibulin-5, MGC108414, UP50, zgc:103575

Protein level used designations for Fibulin 5

  • fibulin-5
  • fibulin 5
  • fibulin-5-like
  • developmental arteries and neural crest EGF-like protein
  • urine p50 protein
  • FIBL-5
  • EVEC
  • dance
  • embryonic vascular EGF repeat-containing protein
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