Fibulin 5 Protein (FBLN5) (AA 1-448) (GST tag)
Aperçu rapide pour Fibulin 5 Protein (FBLN5) (AA 1-448) (GST tag) (ABIN2752787)
Antigène
Voir toutes Fibulin 5 (FBLN5) ProtéinesType de proteíne
Origine
Source
Application
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Attributs du protein
- AA 1-448
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Purification/Conjugué
- Cette Fibulin 5 protéine est marqué à la GST tag.
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Fonction
- FBLN5 (Human) Recombinant Protein (P01)
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Séquence
- MPGIKRILTV TILALCLPSP GNAQAQCTNG FDLDRQSGQC LDIDECRTIP EACRGDMMCV NQNGGYLCIP RTNPVYRGPY SNPYSTPYSG PYPAAAPPLS APNYPTISRP LICRFGYQMD ESNQCVDVDE CATDSHQCNP TQICINTEGG YTCSCTDGYW LLEGQCLDID ECRYGYCQQL CANVPGSYSC TCNPGFTLNE DGRSCQDVNE CATENPCVQT CVNTYGSFIC RCDPGYELEE DGVHCSDMDE CSFSEFLCQH ECVNQPGTYF CSCPPGYILL DDNRSCQDIN ECEHRNHTCN LQQTCYNLQG GFKCIDPIRC EEPYLRISDN RCMCPAENPG CRDQPFTILY RDMDVVSGRS VPADIFQMQA TTRYPGAYYI FQIKSGNEGR EFYMRQTGPI SATLVMTRPI KGPREIQLDL EMITVNTVIN FRGSSVIRLR IYVSQYPF
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Attributs du produit
- Human FBLN5 full-length ORF (BAG52073.1, 1 a.a. - 448 a.a.) recombinant protein with GST tag at N-terminal.
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Purification
- in vitro wheat germ expression system
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
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Conseil sur la manipulation
- Aliquot to avoid repeated freezing and thawing.
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Stock
- -80 °C
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Stockage commentaire
- Best use within three months from the date of receipt of this protein.
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- Fibulin 5 (FBLN5)
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Autre désignation
- FBLN5
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Sujet
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Synonyms: ARMD3,DANCE,EVEC,FIBL-5,FLJ90059,UP50
Gene Description: fibulin 5
Gene Name: FBLN5
Gene Summary: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
GenBank: AK075147.1, BAG52073.1 -
Poids moléculaire
- 76.6 kDa (theoreatical)
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ID gène
- 10516
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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