FZR1 Protéines
(Fizzy/cell Division Cycle 20 Related 1 (FZR1))
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage leads to the ubiquitination of PLK1, preventing entry into mitosis (By similarity).
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custom-made
FZR1
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
FZR1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
FZR1
Origine: Humain
Hôte: Wheat germ
Recombinant
ELISA, WB, AA, AP
1 image
FZR1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
SDS, ELISA, WB
FZR1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
ELISA, WB
custom-made
FZR1
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, ELISA, WB
custom-made
FZR1
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, ELISA, WB
FZR1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
FZR1
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
FZR1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Pseudonymes pour FZR1 Protéines
fizzy and cell division cycle 20 related 1 (Fzr1) Protéinesfizzy/cell division cycle 20 related 1 (CDH1-C) Protéines
fizzy and cell division cycle 20 related 1 (FZR1) Protéines
fizzy-related protein homolog (LOC100027495) Protéines
fizzy-related protein homolog (LOC100179951) Protéines
fizzy/cell division cycle 20 related 1 (Drosophila) (Fzr1) Protéines
fizzy/cell division cycle 20 related 1a (fzr1a) Protéines
AW108046 Protéines
CDC20C Protéines
CDH1 Protéines
Cdh1 Protéines
CDH1-C Protéines
FYR Protéines
Fyr Protéines
FZR Protéines
fzr1 Protéines
FZR2 Protéines
HCDH Protéines
HCDH1 Protéines
zgc:55450 Protéines
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