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FZR1 Protéines

(Fizzy/cell Division Cycle 20 Related 1 (FZR1))

Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage leads to the ubiquitination of PLK1, preventing entry into mitosis (By similarity).

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FZR1 Protein (AA 1-493) (His tag)

custom-made FZR1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Fzr1 Protein, UniprotID Q9R1K5

3 images

N° du produit ABIN7565188

Détails

FZR1 Protein (AA 1-496) (His tag)

custom-made FZR1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant FZR1 Protein, UniprotID Q9UM11

3 images

N° du produit ABIN7553969

Détails

FZR1 Protein (AA 1-493) (GST tag)

FZR1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP

SDS-PAGE (SDS) image for Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-493) protein (GST tag) (ABIN1354593)

SDS

1 image

N° du produit ABIN1354593

Détails

FZR1 Protein (His tag)

FZR1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant SDS, ELISA, WB

N° du produit ABIN7577102

Détails

FZR1 Protein (AA 1-213) (His-IF2DI Tag)

FZR1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

N° du produit ABIN7663772

Détails

FZR1 Protein (AA 1-493) (Strep Tag)

custom-made FZR1 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, ELISA, WB

N° du produit ABIN3137456

Détails

FZR1 Protein (AA 1-496) (Strep Tag)

custom-made FZR1 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, ELISA, WB

N° du produit ABIN3092674