GIT2 Produits
(G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
Catégories
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008].
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Catégories GIT2 en vedette
GIT2 Anticorps
High quality antibodies with extensive validation data.
GIT2 Kits ELISA
Reliable ELISA kits for a wide range of species.
GIT2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GIT2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
N° du produit
ABIN564230
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IP
Validations
- (5)
N° du produit
ABIN564231
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, FACS
Validations
- (4)
N° du produit
ABIN523246
Quantité
50 μg
Fiche technique
Fiche technique
GIT2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648198
Quantité
96 tests
Fiche technique
Fiche technique
GIT2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1355123
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1355125
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3130331
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits GIT2
: "The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation." dans: American journal of physiology. Cell physiology, Vol. 305, Issue 5, pp. C519-28, (2013) (PubMed).: "VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis." dans: PLoS ONE, Vol. 7, Issue 5, pp. e36911, (2012) (PubMed).
: "GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats." dans: PLoS ONE, Vol. 7, Issue 5, pp. e36975, (2012) (PubMed).
: "Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses." dans: PLoS ONE, Vol. 5, Issue 12, pp. e14352, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à GIT2
GIT ArfGAP 2 (GIT2), G protein-coupled receptor kinase interacting ArfGAP 2 (git2), G protein-coupled receptor kinase interacting ArfGAP 2a (git2a), G protein-coupled receptor kinase-interactor 2 (Git2), GIT ArfGAP 2 (Git2), G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog (git2.L), G protein-coupled receptor kinase interacting ArfGAP 2b (git2b), 1500036H07Rik, 5830420E16Rik, 6430510B20Rik, 9630056M03Rik, B230104M05Rik, CAT-2, cat-2, CAT2, git2, mKIAA0148, si:dkey-234h16.4, xgit2, zgc:158416Protein level used designations for GIT2
- ARF GAP GIT2
- ARF GTPase-activating protein GIT2
- G protein-coupled receptor kinase-interactor 2
- GRK-interacting protein 2
- cool-associated, tyrosine phosphorylated protein 2
- cool-interacting tyrosine-phosphorylated protein 2
- G protein-coupled receptor kinase interactor 2
- ARF GTPase activating protein 2
- cool associated tyrosine phosphorylated-2
- G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog
- G protein-coupled receptor kinase interacting ArfGAP 2
- G protein-coupled receptor kinase interactor 2b
- tyrosine-phosphorylated protein CAT-2
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