(Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012].
Crane, Han, Ahn, Oehlke, Kivett, Fedoroff, Butowski, Chang, Clarke, Berger, McDermott, Prados, Parsa: "Individual patient-specific immunity against high-grade glioma after vaccination with autologous tumor derived peptides bound to the 96 KD chaperone protein." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 1, pp. 205-14, (2013) (PubMed).
Pseudonymes pour GRP94 Protéines
heat shock protein 90kDa beta (Grp94), member 1 (hsp90b1) Protéines heat shock protein Hsp90 family protein (grp94) Protéines 94 kD glucose-regulated protein (grp94) Protéines heat shock protein 90 beta family member 1 (HSP90B1) Protéines heat shock protein 90, beta (Grp94), member 1 (Hsp90b1) Protéines heat shock protein 90, beta (grp94), member 1 (hsp90b1) Protéines heat shock protein 90 beta family member 1 (Hsp90b1) Protéines heat shock protein 90kDa beta family member 1 L homeolog (hsp90b1.L) Protéines heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1) Protéines DDBDRAFT_0206450 Protéines DDBDRAFT_0215015 Protéines DDB_0206450 Protéines DDB_0215015 Protéines ecgp Protéines ECGP Protéines endoplasmin Protéines ERp99 Protéines fb61d09 Protéines gp96 Protéines GP96 Protéines Gp96 Protéines grp94 Protéines GRP94 Protéines Grp94 Protéines HSP90B1 Protéines hsp108 Protéines ppk98 Protéines TA-3 Protéines Targ2 Protéines Tra-1 Protéines tra-1 Protéines tra1 Protéines TRA1 Protéines Tra1 Protéines wu:fb61d09 Protéines wu:fq25g01 Protéines