GRP94 Protein (AA 27-799, partial) (His tag)

N° du produit ABIN5712762

Détail du produit

Antigène: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Type de proteíne: Recombinant

Attributs du protein: AA 27-799, partial

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GRP94 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: VDGTVEEDLG KSREGSRTDD EVVQREEEAI QLDGLNASQI RELREKSEKF AFQAEVNRMM KLIINSLYKN KEIFLRELIS NASDALDKIR LISLTDENAL SGNEELTVKI KCDKEKNLLH VTDTGVGMTR EELVKNLGTI AKSGTSEFLN KMTEAQEDGQ STSELIGQFG VGFYSAFLVA DKVIVTSKHN NDTQHIWESD SNEFSVIADP RGNTLGRGTT ITLVLKEEAS DYLELDTIKN LVKKYSQFIN FPIYVWSSKT ETVEEPMEEE EAAKEEKEES DDEAAVEEEE EEKKPKTKKV EKTVWDWELM NDIKPIWQRP SKEVEEDEYK AFYKSFSKES DDPMAYIHFT AEGEVTFKSI LFVPTSAPRG LFDEYGSKKS DYIKLYVRRV FITDDFHDMM PKYLNFVKGV VDSDDLPLNV SRETLQQHKL LKVIRKKLVR KTLDMIKKIA DDKYNDTFWK EFGTNIKLGV IEDHSNRTRL AKLLRFQSSH HPTDITSLDQ YVERMKEKQD KIYFMAGSSR KEAESSPFVE RLLKKGYEVI YLTEPVDEYC IQALPEFDGK RFQNVAKEGV KFDESEKTKE SREAVEKEFE PLLNWMKDKA LKDKIEKAVV SQRLTESPCA LVASQYGWSG NMERIMKAQA YQTGKDISTN YYASQKKTFE INPRHPLIRD MLRRIKEDED DKTVLDLAVV LFETATLRSG YLLPDTKAYG DRIERMLRLS LNIDPDAKVE EEPEEEPEET AEDTTEDTEQ DEDEEMDVGT DEEEETAKES TAE

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Autre désignation: ENPL (HSP90B1 Produits)

Synonymes: ecgp Protein, gp96 Protein, tra1 Protein, grp94 Protein, DDBDRAFT_0206450 Protein, DDBDRAFT_0215015 Protein, DDB_0206450 Protein, DDB_0215015 Protein, TRA1 Protein, HSP90B1 Protein, ERp99 Protein, GRP94 Protein, TA-3 Protein, Targ2 Protein, Tra-1 Protein, Tra1 Protein, endoplasmin Protein, GP96 Protein, fb61d09 Protein, tra-1 Protein, wu:fb61d09 Protein, wu:fq25g01 Protein, Grp94 Protein, ECGP Protein, Gp96 Protein, ppk98 Protein, hsp108 Protein, heat shock protein 90kDa beta (Grp94), member 1 Protein, heat shock protein Hsp90 family protein Protein, 94 kD glucose-regulated protein Protein, heat shock protein 90 beta family member 1 Protein, heat shock protein 90, beta (Grp94), member 1 Protein, heat shock protein 90, beta (grp94), member 1 Protein, heat shock protein 90kDa beta family member 1 L homeolog Protein, hsp90b1 Protein, grp94 Protein, HSP90B1 Protein, Hsp90b1 Protein, hsp90b1.L Protein

Sujet: Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors . Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.1 Publication

Poids moléculaire: 93.2 kDa

UniProt: P14625

Pathways: Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades