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GZMB Produits

(Granzyme B (GZMB))

Catégories

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008].

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Catégories GZMB en vedette

GZMB Anticorps

High quality antibodies with extensive validation data.

GZMB Kits ELISA

Reliable ELISA kits for a wide range of species.

GZMB Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GZMB recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7432145
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, StM
Validations
  • (5)
N° du produit ABIN6939591
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Non-Human Primate
Application FACS
Validations
  • (3)
  • (3)
N° du produit ABIN1302451
Quantité 0.1 mg
Fiche technique Fiche technique

GZMB recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6956298
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6956299
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6956300
Quantité 96 tests
Fiche technique Fiche technique

GZMB recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306264
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306262
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Human Cells
Validations
  • (1)
N° du produit ABIN7320540
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GZMB

Islimye Taskin, Guney, Adali, Hismiogullari, Dodurga, Elmas: "Granzyme B levels and granzyme B polymorphisms in peripheral blood of patients with endometriosis: a preliminary study." dans: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 41, Issue 1, pp. 94-99, (2021) (PubMed).

Qian, Shi, Qi, Zhao, Huang, Han, Zhou, Liu, Liu, Lu, Yuan, Zhao, Kang: "A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors." dans: Theranostics, Vol. 9, Issue 25, pp. 7616-7627, (2020) (PubMed).

Baumann, Dunkel, Schmid, Schmitt, Hiltensperger, Lohr, Laketa, Donakonda, Ahting, Lorenz-Depiereux, Heil, Schredelseker, Simeoni, Fecher, Körber, Bauer, Hüser, Hartmann, Laschinger, Eyerich, Eyerich et al.: "Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal. ..." dans: Nature immunology, Vol. 21, Issue 5, pp. 555-566, (2020) (PubMed).

Bengsch, Ohtani, Khan, Setty, Manne, OBrien, Gherardini, Herati, Huang, Chang, Newell, Bovenschen, Peer, Albelda, Wherry: "Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells." dans: Immunity, Vol. 48, Issue 5, pp. 1029-1045.e5, (2019) (PubMed).

Park, Shin, Kim, Bilsborrow, Mohanty, Montgomery, Shaw, You, Kang: "Transcriptomic analysis of human IL-7 receptor alpha low and high effector memory CD8+ T cells reveals an age-associated signature linked to influenza vaccine response in older adults." dans: Aging cell, Vol. 18, Issue 4, pp. e12960, (2019) (PubMed).

Paidipally, Tripathi, Van, Radhakrishnan, Dhiman, Venkatasubramanian, Devalraju, Tvinnereim, Valluri, Vankayalapati: "Interleukin-21 Regulates Natural Killer Cell Responses During Mycobacterium tuberculosis Infection." dans: The Journal of infectious diseases, Vol. 217, Issue 8, pp. 1323-1333, (2019) (PubMed).

Giles, Hao, Padget, Song, Zhang, Lynes, Sanchez, Liu, Jung, Cao, Fujii, Jensen, Gillespie, Schlom, Gilbert, Nduom, Yang, Lee, Soon-Shiong, Hodge, Park: "Efficient ADCC killing of meningioma by avelumab and a high-affinity natural killer cell line, haNK." dans: JCI insight, Vol. 4, Issue 20, (2019) (PubMed).

Ouni, Gharsalli, Dirix, Braiek, Sendi, Jarraya, Douik El Gharbi, Barbouche, Benabdessalem: "Granzyme B induced by Rv0140 antigen discriminates latently infected from active tuberculosis individuals." dans: Journal of leukocyte biology, Vol. 105, Issue 2, pp. 297-306, (2019) (PubMed).

Gatault, Al-Hajj, Noble, Chevallier, Piollet, Forconi, Gaudy-Graffin, Thibault, Miquelestorena-Standley, Halimi, Büchler, Lemoine, Baron: "CMV-infected kidney grafts drive the expansion of blood-borne CMV-specific T cells restricted by shared class I HLA molecules via presentation on donor cells." dans: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 18, Issue 8, pp. 1904-1913, (2019) (PubMed).

Hartana, Ahlén Bergman, Zirakzadeh, Krantz, Winerdal, Winerdal, Johansson, Alamdari, Jakubczyk, Glise, Riklund, Sherif, Winqvist: "Urothelial bladder cancer may suppress perforin expression in CD8+ T cells by an ICAM-1/TGFβ2 mediated pathway." dans: PLoS ONE, Vol. 13, Issue 7, pp. e0200079, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à GZMB

granzyme B (GZMB), CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT

Protein level used designations for GZMB

  • C11
  • CTLA-1
  • T-cell serine protease 1-3E
  • cathepsin G-like 1
  • cytotoxic T-lymphocyte proteinase 2
  • cytotoxic serine protease B
  • fragmentin 2
  • fragmentin-2
  • granzyme B
  • human lymphocyte protein
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