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Recombinant GZMB anticorps (AA 19-247)

GZMB Reactivité: Humain WB, IHC, ICC, IF (p), mIF Hôte: Lapin Monoclonal BLR022E unconjugated Recombinant Antibody
N° du produit ABIN7449554
  • Antigène Voir toutes GZMB Anticorps
    GZMB (Granzyme B (GZMB))
    Type d'anticorp
    Recombinant Antibody
    Épitope
    • 19
    • 16
    • 13
    • 9
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-247
    Reactivité
    • 122
    • 53
    • 25
    • 10
    • 4
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 77
    • 48
    • 2
    Lapin
    Clonalité
    • 76
    • 51
    Monoclonal
    Conjugué
    • 78
    • 11
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GZMB est non-conjugé
    Application
    • 71
    • 41
    • 40
    • 37
    • 17
    • 17
    • 17
    • 13
    • 13
    • 9
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)
    Fonction
    Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]
    Immunogène
    residues 19-247 (mature protein)
    Clone
    BLR022E
    Isotype
    IgG
    Top Product
    Discover our top product GZMB Anticorps primaire
  • Indications d'application

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 17:40:00

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    GZMB (Granzyme B (GZMB))
    Autre désignation
    Granzyme B (GZMB Produits)
    Synonymes
    anticorps CCPI, anticorps CGL-1, anticorps CGL1, anticorps CSP-B, anticorps CSPB, anticorps CTLA1, anticorps CTSGL1, anticorps HLP, anticorps SECT, anticorps granzyme B, anticorps GZMB
    Sujet
    Background: Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]
    ID gène
    3002
    NCBI Accession
    NP_004122
    UniProt
    P10144
    Pathways
    Apoptose, Caspase Cascade in Apoptosis
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