HIP1 Produits
(Huntingtin Interacting Protein 1 (HIP1))
Catégories
The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Catégories HIP1 en vedette
HIP1 Anticorps
High quality antibodies with extensive validation data.
HIP1 Kits ELISA
Reliable ELISA kits for a wide range of species.
HIP1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HIP1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IP, IHC (p)
Validations
- (7)
- (6)
N° du produit
ABIN561263
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7155937
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, IF
Validations
- (3)
N° du produit
ABIN7262825
Quantité
200 μL
Fiche technique
Fiche technique
HIP1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967472
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956610
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1137580
Quantité
96 tests
Fiche technique
Fiche technique
HIP1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1306634
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1306636
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3092971
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits HIP1
: "Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration." dans: Nature communications, Vol. 5, pp. 3891, (2014) (PubMed).: "Replacement of charged and polar residues in the coiled-coiled interface of huntingtin-interacting protein 1 (HIP1) causes aggregation and cell death." dans: FEBS letters, Vol. 586, Issue 19, pp. 3030-6, (2012) (PubMed).
: "Identification of HYPK-interacting proteins reveals involvement of HYPK in regulating cell growth, cell cycle, unfolded protein response and cell death." dans: PLoS ONE, Vol. 7, Issue 12, pp. e51415, (2012) (PubMed).
: "G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4." dans: Biochemistry, Vol. 50, Issue 32, pp. 6933-41, (2011) (PubMed).
: "Regulation of RE1 protein silencing transcription factor (REST) expression by HIP1 protein interactor (HIPPI)." dans: The Journal of biological chemistry, Vol. 286, Issue 39, pp. 33759-69, (2011) (PubMed).
: "Genome wide gene expression regulation by HIP1 Protein Interactor, HIPPI: prediction and validation." dans: BMC genomics, Vol. 12, pp. 463, (2011) (PubMed).
: "Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1." dans: Nucleic acids research, Vol. 38, Issue 3, pp. 878-92, (2010) (PubMed).
: "Huntingtin interacting protein 1 is a novel brain tumor marker that associates with epidermal growth factor receptor." dans: Cancer research, Vol. 67, Issue 8, pp. 3609-15, (2007) (PubMed).
: "Aberrant Huntingtin interacting protein 1 in lymphoid malignancies." dans: Cancer research, Vol. 67, Issue 18, pp. 8923-31, (2007) (PubMed).
: "The T-box transcription factor T-bet in immunity and autoimmunity." dans: Cellular & molecular immunology, Vol. 3, Issue 2, pp. 87-95, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à HIP1
huntingtin interacting protein 1 (HIP1), Huntingtin interacting protein 1 (Hip1), huntingtin interacting protein 1 (Hip1), huntingtin interacting protein 1 (hip1), 2610109B09Rik, A930014B11Rik, CG10971, Dmel\\CG10971, E130315I21Rik, HIP-I, Hip1R, ILWEQ, mKIAA4113Protein level used designations for HIP1
- huntingtin-interacting protein 1
- huntingtin-interacting protein I
- CG10971-PA
- CG10971-PB
- Hip1-PA
- Hip1-PB
- huntingtin interacting protein 1
- HIP-I
- LOW QUALITY PROTEIN: huntingtin-interacting protein 1
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