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High Mobility Group AT-Hook 1 Produits

(High Mobility Group AT-Hook 1 (HMGA1))

Catégories

This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories High Mobility Group AT-Hook 1 en vedette

High Mobility Group AT-Hook 1 Anticorps

High quality antibodies with extensive validation data.

High Mobility Group AT-Hook 1 Kits ELISA

Reliable ELISA kits for a wide range of species.

High Mobility Group AT-Hook 1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

High Mobility Group AT-Hook 1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, IF, ChIP
Validations
  • (7)
N° du produit ABIN7267646
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, FACS
Validations
  • (1)
  • (4)
N° du produit ABIN653050
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (3)
N° du produit ABIN736626
Quantité 100 μL
Fiche technique Fiche technique

High Mobility Group AT-Hook 1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967399
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956531
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Dog
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956530
Quantité 96 tests
Fiche technique Fiche technique

High Mobility Group AT-Hook 1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1306792
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123326
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306793
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits High Mobility Group AT-Hook 1

Uchikura, Matsubara, Muto, Matsubara, Fujioka, Matsumoto, Sugiyama: "Extranuclear Translocation of High-Mobility Group A1 Reduces the Invasion of Extravillous Trophoblasts Involved in the Pathogenesis of Preeclampsia." dans: Reproductive sciences (Thousand Oaks, Calif.), pp. 1933719117697250, (2017) (PubMed).

Liu, Zhang, Li, Ding, Tu, Zhou, Qi, Chen, Sun: "Let-7a inhibits growth and migration of breast cancer cells by targeting HMGA1." dans: International journal of oncology, Vol. 46, Issue 6, pp. 2526-34, (2015) (PubMed).

Leung, Chan, Ng, Ma, Tse, To, Maranchie, Ho, Lau: "Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer." dans: PLoS ONE, Vol. 9, Issue 5, pp. e98037, (2014) (PubMed).

Di Cello, Shin, Harbom, Brayton: "Knockdown of HMGA1 inhibits human breast cancer cell growth and metastasis in immunodeficient mice." dans: Biochemical and biophysical research communications, Vol. 434, Issue 1, pp. 70-4, (2013) (PubMed).

Lau, Chan, Pang, Ma, Li, Yeung, Cheng, Feng, Chung, Li, Zhou, Wang, Mao, Ng: "Overexpression of HMGA1 deregulates tumor growth via cdc25A and alters migration/invasion through a cdc25A-independent pathway in medulloblastoma." dans: Acta neuropathologica, Vol. 123, Issue 4, pp. 553-71, (2012) (PubMed).

van der Zee, ten Hagen, Hop, van Dekken, Dicheva, Seynhaeve, Koning, Eggermont, van Eijck: "Differential expression and prognostic value of HMGA1 in pancreatic head and periampullary cancer." dans: European journal of cancer (Oxford, England : 1990), Vol. 46, Issue 18, pp. 3393-9, (2010) (PubMed).

Liau, Rocha, Matros, Redston, Whang: "High mobility group AT-hook 1 (HMGA1) is an independent prognostic factor and novel therapeutic target in pancreatic adenocarcinoma." dans: Cancer, Vol. 113, Issue 2, pp. 302-14, (2008) (PubMed).

Chiappetta, Botti, Monaco, Pasquinelli, Pentimalli, Di Bonito, DAiuto, Fedele, Iuliano, Palmieri, Pierantoni, Giancotti, Fusco: "HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2 expression." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 22, pp. 7637-44, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à High Mobility Group AT-Hook 1

high mobility group AT-hook 1 (HMGA1), high mobility group AT-hook 1 (Hmga1), high mobility group protein HMG-I/HMG-Y (TSC_c24220), high mobility group AT-hook 1a (hmga1a), high mobility group protein HMG-I/HMG-Y (LOC705105), high mobility group AT-hook 1b (hmga1b), AL023995, HMG-I(Y), HMG-R, HMG-Y, hmga1, HMGA1, HMGA1A, Hmga1a, Hmga1b, Hmgi, HMGIY, Hmgiy, hmgiy, Hmgy, wu:fb12b06, wu:fb18f11, wu:fc19f01, wu:fi38b05, zgc:85677, zgc:153948

Protein level used designations for High Mobility Group AT-Hook 1

  • HMG-I(Y)
  • high mobility group protein A1
  • high mobility group protein HMG-I/HMG-Y
  • high mobility group protein R
  • high-mobility group (nonhistone chromosomal) protein isoforms I and Y
  • nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y
  • high mobility group AT-hook protein 1
  • high-mobility group AT-hook 1
  • high mobility group AT-hook 1
  • high mobility group HMGA1A
  • high mobility group HMGA1B
  • non-histone protein
  • high mobility group protein I
  • High mobility group AT-hook protein 1
  • High mobility group protein A1
  • high mobility group-I protein
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