HMGCL Produits
(3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))
Catégories
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Catégories HMGCL en vedette
HMGCL Anticorps
High quality antibodies with extensive validation data.
HMGCL Kits ELISA
Reliable ELISA kits for a wide range of species.
HMGCL Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HMGCL recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), ICC, IF
Validations
- (5)
N° du produit
ABIN2856650
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (3)
N° du produit
ABIN561291
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7155995
Quantité
100 μL
Fiche technique
Fiche technique
HMGCL recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1137676
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1137677
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1137678
Quantité
96 tests
Fiche technique
Fiche technique
HMGCL recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN667639
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1306810
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3081488
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits HMGCL
: "β-hydroxybutyrate protects hepatocytes against endoplasmic reticulum stress in a sirtuin 1-independent manner." dans: Archives of biochemistry and biophysics, Vol. 663, pp. 220-227, (2019) (PubMed).: "The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease." dans: Nature medicine, Vol. 21, Issue 3, pp. 263-9, (2015) (PubMed).
: "Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol." dans: Journal of lipid research, Vol. 53, Issue 10, pp. 2046-56, (2012) (PubMed).
: "Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells." dans: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 21, pp. 3956-63, (2012) (PubMed).
: "Differential HMG-CoA lyase expression in human tissues provides clues about 3-hydroxy-3-methylglutaric aciduria." dans: Journal of inherited metabolic disease, Vol. 33, Issue 4, pp. 405-10, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase S homeolog (hmgcl.S), 3-hydroxymethyl-3-methylglutaryl-CoA lyase (HMGCL), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (AFUA_7G01720), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (NFIA_114450), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (ACLA_065820), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (AOR_1_910074), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (PMAA_004600), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (TSTA_103060), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (ARB_04874), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (TRV_06573), 3-hydroxy-3-methylglutaryl-Coenzyme A lyase (Hmgcl), 3-hydroxymethyl-3-methylglutaryl-CoA lyase (Hmgcl), 3-hydroxymethyl-3-methylglutaryl-CoA lyase (hmgcl), Afu7g01720, AO090038000541, AW476067, HL, zgc:56248Protein level used designations for HMGCL
- 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
- 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)
- 3-hydroxy-3-methylglutarate-CoA lyase
- HL
- HMG-CoA lyase
- hydroxymethylglutaryl-CoA lyase, mitochondrial
- 3-hydroxy-3-methylglutaryl-CoA lyase
- hydroxymethylglutaricaciduria
- mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
- 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
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